Le fibrinogen ne mai furotin jini wanda ke taka rawa a ciki narkewar jini. Ya shiga cikin horo na jinin jini Hakanan yana daidaita ayyukan platelet na jini da cell na tasoshin. A karkashin aikin wani furotin, da thrombin, sai ya koma fibrin

Kwayoyin hanta ne ke haɗa shi. Matsayinsa a cikin jini yawanci ya bambanta daga 2 zuwa 4 g / l. Duk da haka, da kira na wannan furotin na iya karuwa a sakamakon damuwa, lokacin daukar ciki, ko bayan allurar wasu magunguna ko hormone girma. Haɓaka matakin fibrinogen a cikin jini kuma yana nuna yanayin kumburi.

Ana nuna gwajin fibrinogen don nunawa don rashin lafiyar jini (misali idan akwai zubar da jini wanda ba a bayyana ba ko " defibrination ciwo », Daidai da rashin daidaituwa na coagulation).

Akwai lahani na haihuwa guda uku a cikin matakan fibrinogen:

• THEafibrinogenemia, wanda shine cikakken rashin fibrinogen. Wannan cuta da ba kasafai ake samunta ba tana haifar da zubar jini mai tsanani da ke fitowa daga haihuwa
• THEhypofibrinogenemia, daidai da raguwar matakin fibrinogen a cikin jini (wannan lahani ne a cikin ɓoye, mafi yawan lokuta)
• La dysfibrinogenemia, wanda shine rashin daidaituwa na furotin.

Hakanan gwajin fibrinogen na jini na iya zama da amfani a lokuta masu zuwa:

• ciwo mai kumburi
• gazawar hanta (wanda ke haifar da raguwar matakan fibrinogen)
• don saka idanu akan tasirin abin da ake kira "fibrinolytic" magani, wanda aka yi niyya don narkar da ƙwayar jini a cikin yanayin thrombosis.

Sashi na fibrinogen ana yin shi ne akan samfurin jini na venous (gwajin jini), a cikin dakin gwaje-gwajen bincike na likita. Sashi shine ma'auni na yau da kullun kuma ana samun sakamako yawanci a cikin rana.

Likita ne kawai zai iya fassara sakamakon binciken.

Yawanci, yawan fibrinogenhyperfibrinogenemia) ana iya lura da shi idan akwai kumburi, idan akwai wasu cututtuka masu yaduwa (naumonia, da dai sauransu), idan akwai zazzabi na rheumatic ko cututtuka na autoimmune (lupus), bayan ciwon zuciya na zuciya, da dai sauransu.

Sabanin haka, hypofibrinogenemia (raguwa a matakin fibrinogen) na iya yin la'akari da cututtuka na kwayoyin halitta, rashin hanta mai tsanani (hepatitis, cirrhosis), rikice-rikice na coagulation (wanda aka yada coagulation na intravascular ko defibrination ciwo) ko "fibrinolysis", misali saboda ciwon daji.