Ana kamuwa da cutar CHIKV ga mutane ta hanyar cizon sauro na jinsin Aedes, wadanda kuma sune ke da alhakin yada cututtukan dengue, zika da zazzabin rawaya. Sauro na iyali guda biyu Aedes suna iya yada kwayar cutar Zika, Aedes aegypti a cikin wurare masu zafi ko yankuna masu zafi, da kuma Aedes albopictus (saron "damisa") a cikin mafi yawan wurare masu zafi.

Sauro (mace ce kawai ke cizon) yana kamuwa da kwayar cutar ta hanyar cizon mai cutar ko dabba sannan kuma yana iya yada cutar ta hanyar cizon wani mutum. Wadancan Aedes suna aiki da yawa a farkon rana da ƙarshen rana.

Kwayar cutar ta CHIKV, idan aka yi wa miji ko mace allurar sauro, takan bazu cikin jini da kuma nodes na lymph, sannan ta kai ga wasu gabobin, musamman tsarin jijiya da gabobi.

Mutumin da ya kamu da chikungunya baya kamuwa da wani mutum kai tsaye. A daya bangaren kuma idan sauro ya sake cije shi Aedes, tana watsa masa kwayar cutar, kuma wannan sauro yana iya yada cutar ga wani.

Yaduwar kwayar cutar chikungunya ta hanyar karin jini ko dashen gabobin jiki zai yiwu, don haka matakan rigakafin da aka dauka don ware masu cutar daga ba da gudummawar jini. Hakanan ana iya yada kwayar cutar daga uwa zuwa jariri yayin daukar ciki ko haihuwa.