Masana kimiyya daga Jami'ar Fasaha ta Lodz sun kirkiro wani sabon suturar hydrogel don maganin raunukan masu ciwon sukari. Tufafin yana ba da tetrapeptide zuwa rauni wanda zai iya dawowa da haifar da sabbin hanyoyin jini a ciki.
A cewar masu binciken, yin amfani da irin wannan suturar na iya rage yawan yanke yanke.
Maganin raunin ciwon sukari a halin yanzu shine matsala mafi girma a Poland da kuma a duniya fiye da maganin wasu nau'in raunuka. Farashin irin waɗannan hanyoyin kwantar da hankali da kuma tasirin zamantakewar cututtukan ciwon sukari suna da yawa - saboda wannan dalili a Poland ana yin jiyya sama da 10 kowace shekara. yanke jiki. Saboda ƙayyadaddun waɗannan raunuka, ba a ƙirƙira wasu abubuwan halitta ba a duniya waɗanda zasu ƙara yuwuwar warakarsu.
Tawagar prof. Janusz Rosiak daga Cibiyar Fasaha ta Radiation Interdepartmental na Jami'ar Fasaha ta Lodz ya haɓaka fasaha don samar da riguna na hydrogel da aka wadatar da tetrapeptide, wanda ke haifar da angiogenesis, watau maido da haifar da sabbin hanyoyin jini a cikin rauni. Gwajin kwayar halitta na irin waɗannan kwayoyin halitta yana ba da sakamako mai kyau.
An ƙirƙiri suturar ne a kan wani suturar hydrogel da masana kimiyya daga Łódź suka haɓaka, wanda - bisa ga fasaharsu - an samar da shi a duk faɗin duniya sama da shekaru 20. Yana da kaddarorin kayan ado mai kyau, kuma godiya gare shi, ana samun kyakkyawan sakamako a cikin maganin raunukan ƙonawa, gadaje da raunuka waɗanda ke da wuyar warkarwa, misali trophic ulcers.
Tufafin Hydrogel da aka yi amfani da shi kai tsaye ga rauni, gami da. yana ba da damar iskar oxygen zuwa rauni, ya zama shinge ga kamuwa da cuta na waje, yana ɗaukar exudates, yana ba da yanayi mai ɗanɗano, yana kawar da ciwo, yana cire ƙwayar necrotic daga rauni lokacin da aka cire shi daga rauni. A lokaci guda, yana ba da damar yin amfani da abubuwan miyagun ƙwayoyi (a cikin wannan yanayin tetrapeptide) a kan tsayayyen ƙima, ba tare da buƙatar sa hannun likita ba.
Da alama maganin da muka samar zai iya zama da amfani sosai wajen magance raunukan masu ciwon sukari. Kudin samar da suturar ya ragu sosai, kuma ana iya aiwatar da samar da shi a zahiri ba tare da babban jari ba - in ji PAP, mahaliccin suturar, Farfesa Janusz Rosiak.
Tufafin don maganin raunukan masu ciwon sukari a halin yanzu yana buƙatar fara gwajin gwaji da na asibiti, waɗanda - a matsayin Farfesa Rosiak - ba gwamnati ce ke ba da kuɗi ba. Wannan shine dalilin da ya sa muke son yin haɗin gwiwa tare da kamfanoni masu sha'awar samar da irin wannan sutura - ya kara da cewa.
A lokacin jiyya tare da suturar hydrogel na gargajiya da aka samar bisa ga hanyar Rosiak, an gano cewa yana da tasiri mai amfani kuma a cikin maganin abin da ake kira ƙafar ciwon sukari, amma yuwuwar warkar da irin wannan rauni tare da yin amfani da irin wannan suturar. kimanin kashi 50 cikin dari. - kamar yadda na sauran nau'ikan suturar da aka sani da amfani da su a duniya.
Wannan yana da alaƙa da ƙayyadaddun raunuka na ciwon sukari, kamar yadda aka bambanta su ta hanyar, da sauransu, necrosis na ƙwayoyin rauni saboda lalacewa da lalata jini. Hakanan yana da alaƙa da lalata ƙwayoyin jijiya da kuma mutuwa a hankali na kyallen da ke kewaye da rauni.
Ƙoƙarin magance irin wannan raunuka, da aka yi a Poland da ma duniya baki ɗaya, ya zo ne don gano nau'in cututtukan ƙwayoyin cuta da kuma amfani da maganin rigakafi ko wasu abubuwa masu aiki waɗanda zasu iya inganta tsabtar raunin. Yayin da ake jiran raunin ya warke, abubuwan da za su iya haifar da angiogenesis, watau farfadowa da samuwar sababbin hanyoyin jini a cikin raunin, za a iya kaiwa gare shi. Don wannan dalili, yin amfani da abubuwa masu yawa, abubuwan da ake kira abubuwan haɓaka.
Farfesa Rosiak ya bayyana cewa a cikin binciken da suka yi, masana kimiyya daga Łódź sun ci karo da rahotanni a cikin wallafe-wallafen game da amfani da tetrapeptide mai sauƙi don haifar da angiogenesis ta hanyar isar da shi zuwa yankin da ake bi da shi na jiki. Abu ne da aka halicce shi ta dabi'a a cikin jikin mutum, yana da ɗan gajeren rabin rayuwa na mintuna 5, don haka maida hankali a cikin kwayoyin halitta mai aiki ya yi ƙasa sosai. An yi rijistar wannan tetrapeptide a matsayin magani kuma Hukumar Abinci da Magunguna ta Amurka (FDA) ta amince da ita.
Duk da haka, gudanarwarsa ga kyallen takarda da ke kewaye da raunin an yi shi ne ta hanyar allura, wanda ya sa ba zai yiwu a sarrafa yankin aikin ba kuma ya haifar da sakamako na yau da kullum - da sauri ya kai babban taro da kuma bacewar sauri daidai, wanda ke lalata tasirin warkewa. Asalin mu, akan sikelin duniya, ra'ayin ya taso ne don ƙoƙarin haɗa suturar hydrogel tare da wannan tetrapeptide - in ji masanin kimiyyar.
Fasahar samar da suturar hydrogel da masu bincike na Łódź suka kirkira ta kunshi samar da cakuda sinadaran da ake sanyawa a cikin ruwa (ruwa ya kai sama da kashi 90 cikin dari na abun da ke ciki), sannan bayan an sanya shi a cikin kunshin sannan a rufe shi, a sanya shi tare da lantarki katako. A sakamakon haka, an kafa facin hydrogel bakararre wanda ake amfani da shi azaman sutura.
Matsalar bincike ita ce ko ba za a lalata sinadarin da ke aiki a lokacin haifuwa ba, saboda tetrapeptide a cikin maganin ruwa a ƙarƙashin tasirin wutar lantarki ya lalace gaba ɗaya a alluran lantarki waɗanda har yanzu basu tabbatar da haifuwar samfurin ba. Koyaya, mun sami nasarar magance wannan matsalar - in ji prof. Rosiak
An gabatar da maganin don kariya a Ofishin Patent. Godiya ga tallafin kudi na Cibiyar Bincike da Ci gaba ta kasa, masana kimiyya daga Lodz sun gudanar da bincike kan motsin motsa jiki na sakin tetrapeptide a cikin rauni, ƙarfin sa a cikin sutura (ana iya amfani dashi ko da shekara guda bayan samarwa) da hulɗa tare da sel.
A matakin kwayoyin halitta, mun tabbatar da maganganun kwayoyin halitta da ke da alhakin angiogenesis, kuma a matakin salula, wani gagarumin haɓakar haɓakar ƙwayoyin endothelial. Mun kuma nuna dogaro da tasirin da aka samu akan tattarawar tetrapeptide kuma mun ƙaddara mafi kyawun sashi - farfesa ya lura.
Masana kimiyya sun sanar da cewa idan ba su sami hanyar samar da kudade don ci gaba da bincike kan suturar ba, ba za su yi watsi da cewa za su bayyana ra'ayinsu a fili ba. Matsalar magance abin da ake kira ƙafar ciwon sukari yana shafar mutane a duk faɗin duniya kuma ba lallai ne mu sami kuɗi a kai ba - in ji Farfesa. Rosiak (PAP)