- Allunan anti-androgen na zamani suna da tasiri sosai - a kusan kowane mataki na jiyya suna iya rage cutar, tsawaita rayuwa kuma ana jure su sosai. Muna magana da Dokta Iwona Skoneczna, PhD, game da sababbin hanyoyin kwantar da hankali na hormone har yanzu ba su da cikakkiyar samuwa ga Poles.
Likita, ciwon daji na prostate ya kasance yana ɗaukar adadin jini akan yawan mace-macen maza na Poland tsawon shekaru. Ɗaya daga cikin dalilan shine "juriya na maza", watau tsoron likitan urologist, ɗayan kuma yana da iyakacin damar samun hanyoyin kwantar da hankali na zamani. Menene marasa lafiyar Poland suka fi rasa?
Yawan rayuwa da mace-mace a cikin neoplasms sun dogara ne akan dalilai da yawa, amma gabaɗaya ana iya cewa mafi mahimmanci shine matakin ci gaban cututtuka a lokacin ganewar asali da kuma ikon yin amfani da kyau, yawanci multidisciplinary, magani. Barkewar cutar ta kara dagula matsalolin bincike na haƙiƙa ga yanayin da galibin mazaje suka rinjayi don yin gwajin urological.
Ina so in sake maimaita cewa ciwon daji na prostate da wuri ba ya haifar da wata alama kuma idan ba mu yi ƙoƙari mu bincika ko ba mu da shi, yana iya ba mu mamaki kuma ya haifar da metastases kafin mu san shi. Wani muhimmin abu da ke haifar da kyakkyawan sakamako na jiyya, musamman a cikin ci gaban ciwon daji na prostate, shine samun hanyoyin kwantar da hankali na zamani. Anan ma, duk da ingantawa, ana iya yin ƙari da yawa.
Ci gaba a cikin maganin ciwon daji na prostate shine zama antiandrogens na zamani - ta yaya suke aiki?
Mun san fiye da shekaru 50 cewa ci gaban ciwon daji na prostate ya dogara ne akan kasancewar kwayoyin halittar namiji, yawanci testosterone. Masu karɓar Androgen a cikin ƙwayoyin kansa suna kama androgens kuma ciwon daji yana girma da sauri. Jiyya na farko shine har yanzu don rage matakan testosterone. A tsawon lokaci, duk da haka, wannan tasirin ya ƙare, kuma ƙwayoyin cutar kansa suna samar da nasu androgens ko kuma su fara haɓaka da kansu.
Ya bayyana, duk da haka, cewa za'a iya toshe mai karɓar androgen na dindindin kuma ci gaban ƙari ya sake raguwa. Allunan anti-androgen na zamani suna da irin wannan sakamako, suna da tasiri sosai, saboda a kusan kowane mataki na jiyya suna iya rage cutar, tsawaita rayuwa kuma ana jure su sosai.
Wadanne marasa lafiya ne za su amfana da sababbin hanyoyin maganin hormone?
A cikin ilimin cututtukan daji, muna ƙoƙarin gano alamun sake dawowa da wuri don samun damar magance haɓakar clones masu juriya da wuri da wuri. A cikin ciwon daji na prostate da aka yi wa tiyata ko radiation far, tashin PSA ya zama alamar farko na komawa. Idan PSA ya ci gaba da karuwa duk da raguwar testosterone, musamman ma lokacin da ya ninka a cikin ƙasa da watanni 10, kuma har yanzu ba mu ga metastases a cikin gwaje-gwajen hoto ba (tomography da kashi scintigraphy), bisa ga ilimin likita, lokaci ya yi da za a yi amfani da sababbin. magungunan hormonal (apalutamide , darolutamide ko enzalutamide). Lokacin da aka ba wa marasa lafiya a wannan mataki, suna jinkirta farawar metastasis da kimanin shekaru 2 kuma suna ƙara kimanin shekara guda zuwa rayuwa gaba ɗaya.
Menene amfanin sabon maganin hormone na baka akan chemotherapy?
Yana da wahala a kwatanta chemotherapy na cikin jijiya tare da na gaba tsara na baka hormone far. Dukansu jiyya suna da amfani kuma yana da kyau a yi amfani da su duka. Yana da kyau a tattauna shirin magani tare da likitan ilimin likitancin, na yanzu da kuma na gaba. Game da cututtukan cututtuka masu tsanani, ana ba da chemotherapy a matsayin magani na farko, yayin da a cikin ƙananan cututtuka na asymptomatic, za mu iya farawa tare da maganin hormone.
Wane ma'auni dole ne majiyyaci ya cika don samun cancantar sababbin hanyoyin maganin cutar kansar prostate a Poland?
Hanyoyin maganin hormone na zamani don ciwon daji na prostate a cikin mataki na juriya ga ragewar testosterone yana samuwa ne kawai ga marasa lafiya waɗanda suka cika ka'idodin cancanta don abin da ake kira shirye-shiryen miyagun ƙwayoyi. A yau, waɗannan alamu ne waɗanda kawai sun haɗa da mutanen da aka tabbatar da metastases, muna jiran lokacin da za mu iya jinkirta bayyanar metastases ta amfani da waɗannan kwayoyi.
Yaya samun magungunan zamani yayi kama da sauran kasashen Tarayyar Turai?
A yawancin ƙasashen EU, ana samun sabbin magungunan hormonal a matakin farko na jiyya fiye da Poland.
Me yasa a ra'ayin ku ba a biya sabbin hanyoyin magance cutar kansar prostate ba kuma akwai wata dama ta canji nan gaba kadan?
Ba zan iya samun amsar tambayar farko ba, kuma ga ta biyu: Ina fata haka.