Wannan cuta mara yaduwa tana da alaƙa da samuwar ma'aunin furotin wanda ke canza aikin al'ada na gabobin. Mafi sau da yawa yana ci gaba zuwa wani nau'i mai tsanani kuma yana iya rinjayar dukkan gabobin. Ba mu san takamaiman adadin mutanen da wannan cuta ba kasafai ta shafa a Faransa ba, amma an kiyasta cewa tana shafar 1 cikin 100 na mutane. (000) Kowace shekara a Faransa, ana gano sabbin maganganu 1 na AL amyloidosis. mafi ƙarancin nau'in cutar.

Adadin Amyloidosis na iya bayyana a kusan kowane nama da gabobin jiki. Amyloidosis yakan ci gaba zuwa wani nau'i mai tsanani ta hanyar lalata gabobin da ya shafa a hankali: koda, zuciya, tsarin narkewa da hanta sune gabobin da suka fi shafa. Amma amyloidosis na iya shafar ƙasusuwa, gidajen abinci, fata, idanu, harshe ...

Saboda haka, kewayon bayyanar cututtuka suna da faɗi sosai: rashin jin daɗi da ƙarancin numfashi lokacin da zuciya ta shiga ciki, edema na ƙafafu game da koda, raguwar sautin tsoka lokacin da jijiyoyi na gefe suka shafi, zawo / maƙarƙashiya da toshewa a cikin yanayin. koda. Maganin narkewar abinci, da dai sauransu. Mummunan alamomin kamar ƙarancin numfashi, gudawa da zubar jini yakamata su faɗakar da su kuma su kai ga tantancewar amyloidosis.

Amyloidosis yana faruwa ne ta hanyar canza tsarin kwayoyin halitta na furotin, yana sa shi rashin narkewa a cikin jiki. Protein sannan ya samar da ma'auni na kwayoyin halitta: abu amyloid. Yana da kyau a yi magana game da amyloidosis fiye da amyloidosis, domin ko da yake wannan cuta tana da dalili iri ɗaya, maganganunta sun bambanta. A zahiri, kusan sunadaran sunadaran sunada alhakin nau'ikan nau'ikan nau'ikan da yawa. Duk da haka, nau'ikan amyloidosis guda uku sun fi rinjaye: AL (immunoglobulinic), AA (mai kumburi) da ATTR (transthyretin).

• AL amyloidosis yana haifar da haɓakar wasu fararen jini (kwayoyin plasma). Suna samar da kwayoyin rigakafi (immunoglobulin) wanda zai tara kuma ya haifar da adibas.
• AA amyloidosis yana faruwa lokacin da kumburi na yau da kullun yana haifar da haɓakar furotin SAA wanda zai haifar da amyloidosis a cikin kyallen takarda.
• Protein transthyretin yana shiga cikin ATTR amyloidosis. Wannan nau'i na cutar shine kwayoyin halitta. Iyaye da abin ya shafa suna da kashi 50% na haɗarin mika maye gurbin ga ɗansu.

Amyloidosis ba ya yaduwa. Bayanan cututtukan cututtuka sun nuna a fili cewa haɗarin yana ƙaruwa da shekaru (amyloidosis yawanci ana gano shi a kusa da shekaru 60-70). Mutanen da ke fama da cututtuka ko kumburi, da kuma waɗanda aka yi wa dialysis na tsawon lokaci, sun fi sauƙi. Kamar yadda wasu nau'o'in amyloidosis, irin su ATTR amyloidosis, ke da alaƙa da maye gurbi na gado, iyalan da ɗaya ko fiye da memba ya shafa dole ne su kasance batun kulawa na musamman.

Har zuwa yau, babu wata hanyar rigakafi don yaƙar amyloidosis. Magungunan duk sun ƙunshi rage samar da furotin mai guba wanda aka adana kuma a haɗa su a cikin kyallen takarda, amma sun bambanta bisa ga nau'in amyloidosis:

• ta hanyar chemotherapy a cikin yanayin AL amyloidosis. Magungunan da aka yi amfani da su wajen maganin sa sun nuna” na ainihin inganci », Ya tabbatar da Ƙungiyar Magungunan Ciki ta Ƙasa (SNFMI), yayin da yake ƙayyade cewa ciwon zuciya ya kasance mai tsanani.
• ta yin amfani da magungunan ƙwayoyin cuta masu ƙarfi don yaƙar kumburin da ya haifar da AA amyloidosis.
• Don ATTR amyloidosis, dasawa na iya zama dole don maye gurbin hanta da aka yi wa mallaka tare da furotin mai guba.

Ƙungiyar Faransanci da Amyloidosis ta wallafa bayanai da yawa game da wannan cuta da jiyya, wanda aka yi nufi ga marasa lafiya da danginsu.