Dalili akai-akai don tuntuɓar, hyperandrogenism yana nufin yawan haɓakar hormones na maza a cikin mace. Ana bayyana wannan ta fiye ko žasa alamun alamun ɓarna.

A cikin mata, ovaries da glandan adrenal suna samar da kwayoyin testosterone, amma a cikin ƙananan yawa. Yawancin lokaci ana samun shi tsakanin 0,3 da 3 nanomoles a kowace lita na jini, idan aka kwatanta da 8,2 zuwa 34,6 nmol / L a cikin mutane.

Muna magana game da hyperandrogenism lokacin da matakin wannan hormone ya fi na al'ada. Alamun virilization na iya bayyanawa: 

• hyperpilosité;
• kuraje;
• gashin gashi;
• tsoka hypertrophy, da dai sauransu.

Tasirin ba kawai kayan ado ba ne. Hakanan yana iya zama na tunani da zamantakewa. Bugu da ƙari, yawan haɓakar testosterone na iya haifar da rashin haihuwa da al'amurran da suka shafi metabolism.

Ana iya bayyana shi ta dalilai daban-daban, mafi yawanci shine masu zuwa.

Ovarian dystrophy

Wannan yana haifar da ciwon ovary polycystic (PCOS). Wannan yana shafar kusan 1 cikin 10 mata. Marasa lafiya suna gano cututtukan su a lokacin samartaka, lokacin da suke tuntuɓar matsalar hauhawar jini da kuraje masu tsanani, ko kuma daga baya, lokacin da suka fuskanci rashin haihuwa. Wannan shi ne saboda yawan adadin testosterone da kwai ke samarwa yana kawo cikas ga ci gaban ɓangarorin ovarian, waɗanda ba su girma ba don sakin qwai. Ana bayyana hakan ne ta hanyar rikice-rikice na al'ada, ko ma ta rashin haila (amenorrhea).

Haihuwar adrenal hyperplasia

Wannan cututtukan da ba kasafai ake samun su ba yana haifar da rashin aiki na adrenal, ciki har da yawan samar da hormones na maza da rashin samar da cortisol, hormone wanda ke taka muhimmiyar rawa a cikin metabolism na carbohydrates, fats da furotin. A wannan yanayin, hyperandrogenism saboda haka yana tare da gajiya, hypoglycemia da raguwar hawan jini. Wannan cutar ta kan bayyana kanta tun daga haihuwa, amma a wasu lokuta masu matsakaicin yanayi yana iya jira har ya girma don bayyana kansa. 

Ciwon daji a kan glandar adrenal

Ba kasafai ba, na iya haifar da wuce gona da iri na hormones na maza, amma kuma cortisol. Hyperandrogenism daga nan yana tare da hypercorticism, ko Cushing's syndrome, tushen hauhawar hauhawar jini.

Wani kumburin ovarian da ke ɓoye hormones na maza

Duk da haka wannan dalilin ba shi da yawa.

menopause

Yayin da samar da hormones na mata ya ragu sosai, hormones na maza suna da damar da za su bayyana kansu. Wani lokaci wannan yana haifar da rushewa, tare da mahimman alamun virilization. Binciken asibiti kawai da ke hade da kima na hormonal, tare da adadin androgens, zai iya tabbatar da ganewar asali. Hakanan ana iya ba da umarnin duban dan tayi na ovaries ko glandan adrenal don bayyana dalilin.

Alamomin asibiti da ke nuna hyperandrogenism sune kamar haka:

• hirsutism : gashi yana da mahimmanci. Musamman, gashi yana fitowa a wuraren da ba su da gashi a cikin mata (fuska, jiki, ciki, baya, gindi, cinyoyin ciki), wanda zai iya yin tasiri mai mahimmanci na tunani da zamantakewa. ;
• kuraje et seborrhea (fatar mai mai); 
• alopecia gashin kansa na namiji, tare da asarar gashi da yawa a saman kai ko na gaba.

Hakanan ana iya haɗa waɗannan alamun da:

• ciwon haila, tare da ko dai rashi na al'ada (amenorrhea), ko dogayen hawan keke da rashin daidaituwa (spaniomenorrhea);
• girman girman clitoral (clitoromegaly) da kuma yawan libido;
• sauran alamun virilization : muryar za ta iya zama mai tsanani kuma musculature yana tunawa da ilimin halittar namiji.

Lokacin da aka yi alama sosai, hyperandrogenism na iya haifar da wasu rikitarwa na dogon lokaci:

• rikitarwa na rayuwa : yawan haɓakar hormones na maza yana inganta haɓakar nauyi da haɓaka juriya na insulin, don haka haɗarin kiba, ciwon sukari da cututtukan zuciya;
• matsalolin gynecological, ciki har da ƙarin haɗarin ciwon daji na endometrial.

Wannan shine dalilin da ya sa bai kamata a yi la'akari da hyperandrogenism kawai daga ra'ayi na kwaskwarima ba. Yana iya buƙatar kulawar likita.

Gudanarwa ya dogara da farko akan dalilin.

Idan akwai kumburi

Ana buƙatar tiyata don cire shi.

Don ciwon ovary polycystic

Babu wani magani da zai hana ko warkar da wannan ciwon, sai dai maganin alamomin sa.

• Idan mai haƙuri bai yi ba ko fiye da yara, maganin ya ƙunshi sanya ovaries su huta, don rage yawan samar da hormones na maza. An rubuta kwayar estrogen-progestin. Idan wannan bai isa ba, ana iya ba da maganin anti-androgen a matsayin kari, cyproterone acetate (Androcur®). Koyaya, tunda kwanan nan an haɗa wannan samfurin tare da haɗarin meningioma, amfani da shi yana iyakance ga mafi girman lokuta, wanda rabon fa'ida / haɗarin yana da inganci;
• A yanayin sha'awar ciki da rashin haihuwa, Sauƙaƙan haɓakar ƙwayar ovulation ana bada shawarar ta layin farko na clomiphene citrate. Ana yin gwajin rashin haihuwa don tabbatar da rashin sauran abubuwan da ke tattare da hakan. Idan motsa jiki ba ya aiki, ko kuma idan an sami wasu dalilai na rashin haihuwa, an yi la'akari da intrauterine insemination ko in vitro hadi. 

Hakanan za'a iya ba da cire gashin Laser don rage girman gashi da maganin dermatological na gida akan kuraje.

A kowane hali, ana ba da shawarar yin wasan motsa jiki da bin tsarin abinci mai daidaitacce. Idan akwai kiba, asarar kusan 10% na nauyin farko yana rage hyperandrogenism da duk rikice-rikicensa. 

Idan akwai hyperplasia adrenal

Lokacin da cutar ta kasance ta kwayoyin halitta, ana ba da kulawa ta musamman a cibiyoyin da suka kware kan cututtuka da ba kasafai ba. Jiyya ya haɗa da corticosteroids musamman.