Masu rushewar endocrine: ina suke ɓoyewa?

Masu rushewar endocrine: ina suke ɓoyewa?

Endocrine disruptor: abin da yake da shi?

Masu rushewar Endocrine sun haɗa da babban iyali na mahadi, na asali ko na roba, masu iya yin hulɗa tare da tsarin hormonal. Don iyakance su, ma’anar Hukumar Lafiya ta Duniya ta 2002 yarjejeniya ce: “Mai yuwuwar cutar da cututtukan endocrine wani abu ne da ba a sani ba ko cakuda, yana da kaddarorin da ke iya haifar da rushewar endocrin a cikin kwayar halitta marar kyau, a cikin zuriyarta. ko a cikin ƙananan jama'a. "

Tsarin hormonal na ɗan adam ya ƙunshi glandar endocrine: hypothalamus, pituitary, thyroid, ovaries, testes, da dai sauransu. Na ƙarshe yana ɓoye hormones, "manzannin sunadarai" wanda ke tsara yawancin ayyuka na physiological na kwayoyin halitta: metabolism, ayyuka na haihuwa, tsarin juyayi, da dai sauransu. Don haka masu rushewar endocrine suna tsoma baki tare da glandon endocrin kuma suna rushe tsarin hormonal.

Idan bincike ya nuna ƙarin sakamako mai lalacewa na yawancin endocrin da ke rushe mahadi akan lafiya da muhalli, kaɗan daga cikinsu sun tabbatar da cewa su zama "masu rushewar endocrin" a yau. Duk da haka, da yawa ana zargin suna da irin wannan aiki.

Kuma saboda kyakkyawan dalili, yawan guba na fili ta hanyar rushewar tsarin endocrine ya dogara da sigogi daban-daban:

  • Matsakaicin bayyanarwa: ƙarfi, rauni, na yau da kullun;

  • Abubuwan da ke canzawa: haɗarin kiwon lafiya na iya ba kawai damuwa da wanda aka fallasa ba, har ma da zuriyarsu;

  • Tasirin Cocktail: jimlar mahadi da yawa a ƙananan allurai - wani lokacin ba tare da haɗari ba lokacin da aka ware - na iya haifar da illa mai lalacewa.

    • Hanyoyin aiki na masu rushewar endocrine

    Duk hanyoyin aiwatar da ayyukan masu rushewar endocrine har yanzu sune batun bincike da yawa. Amma sanannun hanyoyin aiki, waɗanda suka bambanta bisa ga samfuran da aka yi la'akari, sun haɗa da:

    • gyare-gyaren samar da kwayoyin halitta - estrogen, testosterone - ta hanyar tsoma baki tare da hanyoyin haɗin gwiwar su, sufuri, ko fitarwa;

  • Yana kwaikwayi aikin hormones na halitta ta hanyar maye gurbin su a cikin hanyoyin nazarin halittu da suke sarrafawa. Wannan sakamako ne na agonist: wannan shine lamarin tare da Bisphenol A;

  • Kashe ayyukan hormones na halitta ta hanyar haɗa kansu ga masu karɓa wanda yawanci suke hulɗa da su kuma ta hanyar hana watsa siginar hormonal - wani sakamako na gaba.

    • Tushen bayyanar cututtuka ga masu rushewar endocrine

    Akwai hanyoyi da yawa na fallasa ga masu rushewar endocrine.

    Chemicals da masana'antu ta-kayayyakin

    Tushen farko, mai faɗin gaske ya shafi sinadarai da samfuran masana'antu. Fiye da samfura dubu, na nau'ikan sinadarai iri-iri, an jera su. Daga cikin mafi yawansu akwai:

    • Bisphenol A (BPA), ingested saboda yana cikin abinci da robobi marasa abinci: kwalabe na wasanni, ƙwararrun hakori da haƙoran hakora, kwantena don masu rarraba ruwa, kayan wasan yara, CD da DVD, ruwan tabarau na ido, kayan aikin likita, kayan aiki, kwantena filastik. , gwangwani da gwangwani na aluminum. A cikin 2018, Hukumar Tarayyar Turai ta saita ƙayyadaddun ƙayyadaddun ƙaura don BPA a 0,6 milligrams a kowace kilogiram na abinci. Hakanan an haramta amfani da shi a cikin kwalabe na jarirai;

  • Phthalates, rukuni na sinadarai na masana'antu da ake amfani da su don yin robobi masu wuya kamar polyvinyl chloride (PVC) mafi sauƙi ko sassauƙa: labulen shawa, wasu kayan wasan yara, suturar vinyl, jakunkuna na fata da tufafi, kayan aikin biomedicals, samfuran salo, kulawa da samfuran kwaskwarima da turare. A Faransa, an hana amfani da su tun ranar 3 ga Mayu, 2011;

  • Dioxins: nama, kayan kiwo, kifi da abincin teku;

  • Furans, ƙananan ƙwayoyin cuta da aka samu yayin aikin dumama abinci, kamar dafa abinci ko haifuwa: gwangwani na ƙarfe, kwalban gilashi, abinci mai cike da ruwa, gasasshen kofi, kwalban jarirai…;

  • Polycyclic aromatic hydrocarbons (PAHs), sakamakon rashin cikar konewar kayan halitta kamar kayan wuta, itace, taba: iska, ruwa, abinci;

  • Parabens, masu kiyayewa da aka yi amfani da su a yawancin samfurori: magunguna, kayan shafawa, kayan tsabta da masana'antun abinci;

  • Organochlorines (DDT, chlordecone, da dai sauransu) da aka yi amfani da su a cikin kayan kariya na shuka: fungicides, magungunan kashe qwari, herbicides, da dai sauransu;

  • Butylated hydroxyanisol (BHA) da butylhydroxytoluene (BHT), abinci Additives da hadawan abu da iskar shaka: creams, lotions, moisturizers, lebe balms da sandunansu, fensir da ido inuwa, abinci marufi, hatsi, taunawa, nama , margarine, miya da sauran dehydrated abinci…;

  • Alkylphenols: fenti, kayan wanka, magungunan kashe qwari, bututun famfo na PVC, kayan canza launin gashi, kayan shafa na bayan gida, goge goge, goge-goge, maniyyi…;

  • Cadmium, carcinogen da ke cikin ciwon huhu: robobi, yumbu da gilashin launi, ƙwayoyin nickel-cadmium da batura, kwafi, PVC, magungunan kashe qwari, taba, ruwan sha da kayan aikin lantarki; amma kuma a cikin wasu abinci: waken soya, abincin teku, gyada, tsaba sunflower, wasu hatsi da madarar shanu.

  • Brominated harshen wuta retardants da Mercury: wasu masana'anta, furniture, katifa, lantarki kayayyakin, motoci, ma'aunin zafi da sanyio, fitulun fitilu, batura, wasu creams walƙiya fata, antiseptic creams, ido drops, da dai sauransu.;

  • Triclosan, wani roba Multi-application antibacterial, antifungal, antiviral, anti-tartar da preservative, samuwa a cikin da yawa kayayyakin kamar: sabulu, man goge baki, taimakon farko da kuma kuraje kayayyakin, kayan shafawa, aski creams, moisturizing lotions, kayan shafa cirewa, deodorants, shawa. labule, soso na kicin, kayan wasan yara, kayan wasanni da wasu nau'ikan robobi;

  • Gubar: batirin abin hawa, bututu, kebul na USB, kayan lantarki, fenti akan wasu kayan wasan yara, pigments, PVC, kayan ado da gilashin crystal;

  • Tin da sauran abubuwan da ake amfani da su, ana amfani da su wajen kaushi;

  • Teflon da sauran perfluorinated mahadi (PFCs): wasu creams na jiki, jiyya ga kafet da yadudduka, abinci marufi da dafa abinci, wasanni da likita kayan aiki, ruwa mai hana ruwa, da dai sauransu;

  • Kuma da yawa

    • Hormones na halitta ko na roba

    Babban tushe na biyu na masu rushewar endocrine sune hormones na halitta - estrogen, testosterone, progesterone, da dai sauransu - ko kira. Maganin hana haihuwa, maye gurbin hormonal, maganin hormone… Ana amfani da samfuran roba waɗanda ke kwaikwayi tasirin hormones na halitta a magani. Koyaya, waɗannan hormones suna haɗuwa da yanayin yanayi ta hanyar sharar ɗan adam ko dabba.

    A Faransa, Hukumar Kula da Abinci, Muhalli da Kare Lafiyar Ma'aikata (ANSES) ta ƙaddamar da buga ta 2021 jerin duk masu rushewar endocrine…

    Tasiri da kasada na masu rushewar endocrine

    Sakamakon da zai iya haifar da jiki, musamman ga kowane mai rushewar endocrine, yana da yawa:

    • Rashin lahani na ayyukan haihuwa;

  • Malformation na gabobin haihuwa;

  • Rushewar aikin thyroid, haɓakar tsarin juyayi da haɓaka fahimta;

  • Canji a cikin rabon jima'i;

  • ciwon.

  • Kiba da ciwon hanji;

  • Hormone-dogara cancers: ci gaban ciwace-ciwacen daji a cikin kyallen takarda da cewa samar ko manufa hormones - thyroid, nono, testes, prostate, mahaifa, da dai sauransu;

  • Kuma da yawa

    • Nunin in utero na iya haifar da mummunan sakamako ga dukan rayuwa:

    • A kan tsarin kwakwalwa da aikin tunani;

  • A farkon balaga;

  • Kan ka'idojin nauyi;

  • Kuma akan ayyukan haihuwa.

    • Endocrine disrupters da Covid-19

    Bayan wani bincike na farko na Danish wanda ke nuna rawar da aka lalata a cikin tsananin Covid-19, na biyu ya tabbatar da shigar masu rushewar endocrine cikin tsananin cutar. An buga shi a cikin Oktoba 2020 ta ƙungiyar Inserm da Karine Audouze ke jagoranta, ya bayyana cewa fallasa ga sinadarai masu kawo cikas ga tsarin endocrin na iya tsoma baki tare da siginar halittu daban-daban a cikin jikin ɗan adam suna taka muhimmiyar rawa a cikin tsananin cutar. Cutar covid19.

    Endocrine disruptors: yadda za a hana su?

    Idan yana da wuya a tsere wa masu rushewar endocrine, wasu kyawawan halaye na iya taimakawa wajen kare su ko da kaɗan:

    • Favors robobi da aka yi la'akari da su zama lafiya: High Density Polyethylene Ko High Density Polyethylene (HDPE), Low Density Polyethylene Ko Low Density Polyethylene (LDPE), Polypropylene (PP);

  • Hana robobin da ke ɗauke da masu rushewar endocrine waɗanda aka tabbatar da haɗarinsu: Polyethylene Terephthalate (PET), Polyvinyl Chloride (PVC);

  • Kauce wa robobi tare da pictograms: 3 PVC, 6 PS da 7 PC saboda karuwar cutarwa a ƙarƙashin tasirin zafi;

  • Ban Teflon pans da ni'ima bakin karfe;

  • Yi amfani da kwantena gilashi ko yumbu don tanda microwave da kuma ajiya;

  • A wanke 'ya'yan itatuwa da kayan marmari don kawar da yawancin magungunan kashe qwari kamar yadda zai yiwu da kuma fifita samfurori daga aikin noma;

  • Kauce wa additives E214-219 (parabens) da E320 (BHA);

  • Karanta a hankali lakabin kayan tsabta da kayan ado, yarda da alamun kwayoyin halitta kuma a hana wadanda ke dauke da wadannan mahadi: Butylparaben, propylparaben, sodium butylparaben, sodium propylparaben, potassium butylparaben, potassium propylparaben, BHA, BHT, Cyclopentasiloxane, cyclotetrasiloxane, cyclomethiconeyl, Ethylnaxixmate Benzophenone-1, benzophenone-3, Triclosan, da dai sauransu;

  • Cire magungunan kashe qwari (fungicides, herbicides, maganin kwari, da sauransu);

  • Kuma da yawa

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