Michael Greger, MD, Maris 27, 2014
Me yasa yawan cin kayan lambu akai-akai yana ze yanke yiwuwar rashin damuwa da fiye da rabi?
A cikin 2012, masu bincike sun gano cewa kawar da kayan dabba ya inganta yanayi na makonni biyu. Masu bincike suna zargin arachidonic acid, wanda aka samu galibi a cikin kaji da ƙwai, don mummunan tasiri akan lafiyar hankali. Wannan acid yana haifar da haɓakar kumburin kwakwalwa.
Amma haɓakar yanayi na tushen shuka na iya kasancewa saboda phytonutrients da ake samu a cikin tsire-tsire, waɗanda ke haye shingen jini-kwakwalwa a cikin kawunanmu. Wani bita na baya-bayan nan a cikin mujallar Nutritional Neuroscience ya nuna cewa cin 'ya'yan itatuwa da kayan marmari na iya wakiltar wani nau'in cutarwa na halitta da mara tsada da rigakafin cututtukan kwakwalwa. Amma ta yaya?
Don fahimtar sabon bincike, muna buƙatar sanin ilimin halitta na ciki na ciki, abin da ake kira ka'idar monoamine na ciki. Wannan ra'ayin shi ne baƙin ciki na iya tasowa daga rashin daidaituwar sinadarai a cikin kwakwalwa.
Hanya daya da biliyoyin jijiyoyi da ke cikin kwakwalwarmu za su iya sadarwa da juna ita ce ta hanyar shiga tsakani na siginar sinadarai da ake kira neurotransmitters. Kwayoyin jijiya biyu ba sa taɓa gaske - akwai tazara ta jiki a tsakanin su. Don cike wannan gibin, lokacin da wata jijiyar ke son ta harba wani, sai ta saki sinadarai a cikin wannan gibin, ciki har da monoamines guda uku: serotonin, dopamine, da norepinephrine. Wadannan na'urori masu kwakwalwa sai su yi iyo zuwa wata jijiyar don samun hankalinsa. Jijiya ta farko ta sake tsotsa su don sake amfani da ita a lokaci na gaba yana son magana. Har ila yau, yana samar da monoamines da enzymes, monoamine oxidases, kullum yana sha su kuma yana kula da adadin da ya dace.
Ta yaya cocaine ke aiki? Yana aiki a matsayin mai hana sakewa na monoamine. Yana toshe jijiyar farko, yana hana shi tsotse baya da waɗannan sinadarai guda uku waɗanda ake tilastawa kullun a kan kafada kuma akai-akai suna sigina zuwa tantanin halitta na gaba. Amphetamine yana aiki kamar haka amma kuma yana ƙara sakin monoamines. Ecstasy yana aiki kamar amphetamine, amma yana haifar da mafi girman sakin serotonin.
Bayan ɗan lokaci, jijiya na gaba na iya cewa, “Ya isa!” kuma ku danne masu karɓar ku don rage ƙarar. Wannan yana kwatankwacin saƙon kunne. Don haka dole ne mu kara shan kwayoyi don samun irin wannan sakamako, sannan idan ba mu samu ba, za mu iya jin dadi saboda yada kwayar cutar ta yau da kullun ba ta shiga.
Ana tsammanin magungunan rage damuwa sun haɗa da irin wannan hanyoyin. Mutanen da ke fama da baƙin ciki sun haɓaka matakan monoamine oxidase a cikin kwakwalwa. Yana da wani enzyme wanda ke rushe neurotransmitters. Idan matakan neurotransmitter ɗinmu sun ragu, za mu kasance cikin baƙin ciki (ko haka ka'idar ta tafi).
Don haka, an ƙirƙiri nau'ikan magunguna daban-daban. Magungunan antidepressants na tricyclic suna toshe reuptake na norepinephrine da dopamine. Sannan akwai SSRIs (Masu hana masu hanawa na Serotonin Reuptake), kamar Prozac. Yanzu mun san abin da ake nufi - kawai suna toshe sake dawo da serotonin. Akwai kuma magungunan da kawai ke toshe reuptake na norepinephrine, ko kuma toshe reuptake na dopamine, ko haɗin duka biyun. Amma idan matsalar ta yi yawa monoamine oxidase, me yasa ba kawai toshe enzyme ba? Yi monoamine oxidase masu hanawa. Sun yi, amma monoamine oxidase inhibitors ana la'akari da kwayoyi tare da mummunan suna saboda mummunan sakamako masu illa wanda zai iya zama mai mutuwa.
Yanzu zamu iya magana game da sabuwar ka'idar dalilin da yasa 'ya'yan itatuwa da kayan marmari zasu iya inganta yanayin mu. Ana samun masu hana damuwa a cikin tsire-tsire daban-daban. Kayan yaji kamar su cloves, oregano, kirfa, nutmeg suna hana monoamine oxidase, amma mutane ba sa cin kayan yaji don warkar da kwakwalwar su. Taba yana da irin wannan tasiri, kuma wannan na iya kasancewa ɗaya daga cikin dalilan haɓaka yanayi bayan shan taba sigari.
To, amma idan ba ma son musanya mugun yanayi don ciwon huhu fa? Mai hana monoamine oxidase wanda aka samu a cikin apples, berries, inabi, kabeji, albasa, da koren shayi na iya shafar ilimin halittar kwakwalwar mu a zahiri don inganta yanayin mu, kuma yana iya taimakawa wajen bayyana dalilin da yasa waɗanda suka fi son abinci na tushen shuka sukan sami mafi girman hankali. maki lafiya.
Sauran magungunan su na dabi'a don tabin hankali na iya ba da shawarar saffron da lavender.