Acromegaly cuta ce ta haifar da haɓakar haɓakar hormone girma (wanda kuma ake kira somatotropic hormone ko GH for Growth Hormon). Wannan yana haifar da canji a fuskar fuska, ƙaruwa da girman hannaye da ƙafafu da ma gabobin da yawa, waɗanda sune sanadin manyan alamomi da alamun cutar.

Yanayi ne da ba a saba gani ba, yana shafar kusan mutane 60 zuwa 70 a cikin mazaunan miliyan guda, wanda ke wakiltar shari'o'i 3 zuwa 5 a cikin miliyoyin mazauna kowace shekara.

A cikin manya, galibi ana gano shi tsakanin shekarun 30 zuwa 40. Kafin balaga, karuwar GH yana haifar da gigantism ko giganto-acromegaly.

Babban abin da ke haifar da acromegaly shine kumburin mara kyau (wanda ba mai cutar kansa ba) na glandan pituitary, gland (wanda kuma ake kira glandan pituitary), wanda ke cikin kwakwalwa kuma wanda ke asirce da yawa hormones ciki har da GH.