Za a iya ƙayyade yawan adadin uric acid a cikin jini ko a cikin fitsari. Don wuce gona da iri, galibi alama ce ta gout, yawan shan barasa ko gazawar koda.

Uric acid shine a Sharar gida na jiki. Musamman, shine ƙarshen samfurinfitarwa kwayoyin da ake kira nucleic acid da purines.

Galibi mafi yawan sinadarin uric acid dake cikin jikin dan adam yana narkewa a cikin jini kuma yana shiga cikin koda domin kawar da shi a cikin fitsari. Amma a wasu lokuta, jiki yana samar da uric acid da yawa ko kuma ya kasa cire isashensa. Wannan yanayin zai iya zama sanadin cututtuka daban-daban.

Uric acid shine ƙarshen samfurin lalacewa na slurry, ƙimar sa ya bambanta dangane da abun cikin purine a cikin jiki. Kuma ya bayyana cewa ana samun purines musamman a cikin abinci. 

Wasu daga cikin abincin da ke da sinadarin purines don gujewa su ne:

• anchovies, herring, mackerel, sardines, shrimps, da dai sauransu;
• hanta, zuciya, kwakwalwa, koda, gurasa mai dadi, da sauransu;
• wake, busasshen wake, da sauransu.

Ba a ba da shawarar shan barasa, musamman giya, lokacin da kake son rage uric acid.

Sabanin haka, a cikin abincin da aka halatta masu ƙarancin purine, zamu iya ambata:

• shayi, kofi, abubuwan sha masu laushi;
• 'ya'yan itatuwa da kayan marmari;
• qwai;
• gurasa da hatsi;
• cuku da sauran kayan kiwo gabaɗaya

Me yasa ake gwajin uric acid?

Likitan ya rubuta gwajin jini (wanda ake kira uricemia) da / ko gwajin uric acid na fitsari don:

• gano gout;
• tantance yadda kodan ke aiki sosai;
• Hakanan za'a iya nema a yayin da ake ciki;
• ko a cikin mutane masu kiba.

A lura cewa nazarin yawan uric acid a cikin fitsari zai kuma ba da damar fahimtar asalin yawan uric acid a cikin jini.

A cikin jini, ƙimar al'ada na uric acid tsakanin 35 zuwa 70 mg / L.

Ana kiran ƙara yawan uric acid a cikin jini hyperuricemia kuma ana iya haifar da shi ta hanyar yawan sinadarin uric acid a cikin jiki ko kuma ta hanyar raguwar kawar da shi ta hanyar koda. Don haka, yawan adadin uric acid a cikin jini na iya zama alamar:

• gout (wannan shine babban dalilin karuwa a matakin uric acid a cikin jini);
• wuce haddi na lalata sunadaran kwayoyin halitta wanda ke faruwa, alal misali, a lokacin chemotherapy, cutar sankarar bargo ko ma lymphoma;
• shaye-shaye;
• motsa jiki mai yawa;
• kasancewar duwatsun koda;
• saurin asarar nauyi;
• ciwon sukari;
• abinci mai arziki a cikin purine;
• preeclampsia a lokacin daukar ciki;
• ko gazawar koda.

Sabanin haka, yana yiwuwa matakin uric acid na jini ya yi ƙasa da na al'ada, amma wannan yanayi ne mai wuya fiye da yanayin inda ya ƙare sama.

Don haka, matakan uric acid da ke ƙasa da ƙimar al'ada na iya zama alaƙa da:

• wani low-purine rage cin abinci;
• Cutar Wilson (cutar kwayoyin halitta wanda jan karfe ke taruwa a cikin jiki);
• koda (irin su Fanconi ciwo) ko lalacewar hanta;
• ko ma fallasa ga mahadi masu guba ( gubar).

A cikin fitsari, ƙimar al'ada na uric acid tsakanin 250 zuwa 750 mg / awa 24.

Lura cewa ƙimar al'ada na iya bambanta kaɗan dangane da dakunan gwaje -gwajen da ke yin nazarin.

Yana shafar kashi 5 zuwa 15% na yawan jama'a, rashin daidaituwar sinadarai ne na yau da kullun, sakamakon yawan haɓakar uric acid da / ko rage kawar da koda. Sau da yawa yana tasowa ba tare da jin zafi ba saboda haka ba koyaushe ake gano shi ba.

Ana iya bayyana yawan matakan uric acid ta:

Idiopathic ko na farko hyperuricemia

Suna wakiltar mafi yawan lokuta. Ana samun tsinkayar gado a cikin kashi 30% na batutuwa, amma galibi ana danganta su da kiba, yawan cin abinci, hawan jini, shan barasa, ciwon sukari da hypertriglyceridemia.

Rare enzyme abnormalities

Ana samun su musamman a cutar Von Gierke da cutar Lesch-Nyhan. Wadannan rashin daidaituwa na enzymatic suna da musamman na haifar da harin gout da wuri, watau a cikin shekaru 20 na farko na rayuwa.

Hyperuricemia na biyu zuwa cuta ko magani.

Hyperuricemia na iya zama saboda:

- rashin kawar da uric acid. Wannan shi ne yanayin gazawar koda, amma kuma saboda wasu magunguna (diuretics, amma har da laxatives da wasu magungunan rigakafin tarin fuka).

- karuwa a cikin lalacewa na nucleic acid. Muna ganin wannan a cikin cututtukan jini (cututtukan sankarar jini, hemopathies, anemia hemolytic, psoriasis mai yawa), da kuma sakamakon wasu cututtukan cututtukan daji.

Sakamakon hyperuricemia

Hyperuricemia na iya haifar da matsaloli iri biyu:

• Gout da ke da alhakin ciwon haɗin gwiwa-nau'in kumburi.

Lokacin da microcrystals na uric acid da aka narkar da a cikin jini suna da yawa sosai kuma yanayin gida yana da kyau (musamman ma isasshen acidity na matsakaici), suna haɓakawa kuma suna haifar da kumburi na gida. Wannan zai fi dacewa yana shafar haɗin gwiwa na babban yatsan yatsa. Mutum 1 cikin 10 na mutanen da ke da yawan uric acid a cikin jininsu za su samu gout, don haka kana bukatar karin saukin kamuwa don samunsa.

• Urinary lithiasis.

Sun kasance saboda kasancewar daya ko fiye da duwatsu a cikin urinary fili kuma suna da alhakin colic na renal. Urolithiasis cuta ce ta gama gari tun da kashi 1 zuwa 2% na yawan jama'a na fama da cutar a Faransa.

Ana iya yin nazarin matakin acid guda ɗaya a cikin jini da / ko a cikin fitsari:

• gwajin jini ya ƙunshi samfurin jini na venous, yawanci a cikin maƙarƙashiya na gwiwar hannu;
• Ana auna matakin uric acid a cikin fitsari sama da sa'o'i 24: don yin haka, ya isa a yi fitsari a cikin akwati da aka tanada don wannan dalili kuma ma'aikatan kiwon lafiya sun ba su kwana ɗaya da dare ɗaya.

Lura cewa yana da kyau kada a ci ko sha wani abu a cikin sa'o'in da ke gaban gwajin.

Akwai abubuwa da yawa da zasu iya shafar matakin uric acid a cikin jini ko a cikin fitsari. Waɗannan sun haɗa da:

• abinci (malauci ko babba a cikin purines);
• kwayoyi (don shiga gout, aspirin, ko ma diuretics);
• shekaru, yara da ƙananan dabi'u;
• jinsi, tare da mata gabaɗaya suna da ƙarancin ƙima fiye da maza;
• nauyi, mutane masu kiba suna da ƙimar girma.

Jiyya na miyagun ƙwayoyi idan hyperuremia alama ce kamar haka: 

• Nucleic acid masu rage kira, kamar allopurinol. Dole ne ku kasance a faɗake sosai saboda akwai hulɗa da yawa tare da wasu magunguna.
• Magungunan da ke hana sake dawowar uric acid na koda, kamar benzbromaron.
• Magungunan enzymatic waɗanda galibi suna haifar da matsalolin rashin lafiyan.

Duk abin da ya faru, likita ne ya yanke shawarar ko ya kamata a bi magani, kuma wanda ya fi dacewa.