1) yana da alaƙa da haɓaka haɓakar hormone girma

- Alamomin acromegaly suna da alaƙa, da farko, zuwa sakamakon haɓakar haɓakar haɓakar GH da na wani hormone, IGF-1 (Insulin Growth Factor-1) wanda GH ke sarrafawa:

Sun fahimta:

• karuwa a girman hannaye da ƙafafu;

• canji a fuskar fuska, tare da zagayen gaba, fitattun kunci da gandun gira, hanci mai kauri, kaurin lebe, ratar hakora, harshe mai kauri, chin "galoche";

• ciwon haɗin gwiwa (arthralgia) ko ciwon baya (jin zafi na kashin baya), tingling ko tingling a cikin hannayen da ke hade da ciwon ramin carpal saboda kaurin kashi a cikin wuyan hannu yana matsawa jijiyar tsakiya;

• wasu alamomi, kamar yawan zufa, gajiya, rashin ji, canjin murya, da sauransu.

2) dangane da sanadi

- Other bayyanar cututtuka suna da nasaba da hanyar, cewa shi ne ya ce, mafi sau da yawa zuwa ga benign ƙari na pituitary gland shine yake da, ta kara girma daga cikin karshen, za a iya damfara sauran kwakwalwa Tsarin da / ko rage samar da wasu pituitary hormones:

• ciwon kai (ciwon kai);

• damuwa na gani;  

• raguwa a cikin siginar hormones na thyroid yana haifar da sanyi, jinkirin gaba ɗaya, maƙarƙashiya, raguwar bugun zuciya, karuwar nauyi, wani lokaci tare da kasancewar goiter;

• raguwa a cikin ɓoyewar hormones na adrenal (gajiya, asarar ci, raguwa a cikin girma gashi, hypotension, da dai sauransu);

• raguwar fitowar kwayoyin halittar jima'i (rashin jinin haila, rashin karfin jiki, rashin haihuwa, da sauransu).

 3) Sauransu

- Yawan wuce haddi na GH a wasu lokuta yana tare da haɓakar haɓakar wani hormone, prolactin, wanda zai iya haifar da haɓakar nono a cikin maza (gynecomastia), zubar da madara da raguwar sha'awar jima'i a cikin mata da maza, tsawo ko dakatar da hawan haila a cikin mata ...

- Acromegaly sau da yawa yana tare da wasu cututtuka irin su ciwon sukari, hawan jini, bugun zuciya, duwatsu masu gallbladder, nodules, har ma da ciwon daji na thyroid, kuma akwai kuma yawan ciwon daji na hanji, saboda haka ana buƙatar ƙarin bincike a wasu lokuta (ultrasound na thyroid, kimantawar barci na barci, colonoscopy, da dai sauransu).

Alamun suna bayyana sannu a hankali, don haka ana yin ganewar asali ne kawai bayan shekaru da yawa na ci gaba (daga 4 zuwa fiye da shekaru 10). Ana yin sau da yawa da farko a kan bayyanar jiki, lokacin da abin ya shafa (ko tawagarsa) ya lura cewa ba zai iya saka zoben sa ba, ya canza girman takalma da girman hula. 

Wani lokaci, kuma, waɗannan hotuna ne da ke ba da haske game da sauye-sauyen da ba a saba gani ba a fuska a kan lokaci.