MPV: babba ko ƙarami, ma'anar ƙarar platelet

The MPV, ma'ana ƙarar platelet, shine a index size platelet, wanda ya zama mafi ƙanƙan abubuwan da ke cikin jini kuma su ma abubuwa ne masu aiki sosai. Platelets kuma ana kiranta thrombocytes.

• Platelets suna da amfani ga ƙin jini. Suna shiga cikin dakatar da zub da jini yayin canza bangon jijiyoyin jini (arteries ko veins). Ana kunna su a yayin zubar da jini na cikin gida kamar lokacin zubar da jini na waje;
• Ana samar da platelets a cikin kasusuwan kasusuwa, inda babbar tantanin halitta (wanda ake kira megakaryocyte) ta fashe cikin dubban ƙananan gutsutsuren. Waɗannan gutsutsuren, waɗanda ake kira platelets, suna aiki da zarar sun shiga cikin jini;
• Yana yiwuwa a ƙidaya platelet, amma kuma don auna ƙarar su ta hanyar mai nazari ta amfani da katako mai haske.

Manyan platelet yawanci ƙarami ne, kuma an sake su da wuri fiye da yadda aka saba daga kasusuwan ƙashi. Sabanin haka, ƙaramin-matsakaicin platelet gaba ɗaya ya tsufa.

A al'ada akwai sabanin alaƙa tsakanin ma'anar ƙarar platelet (MPV) da kuma adadin platelets. Akwai, don haka, tsarin halitta na jimlar adadin platelet (haɗin lamba da girman platelet). Wannan yana nuna cewa raguwar adadin platelet yana haifar da kuzarin megakaryocytes ta hanyar thrombopoietin, wanda ke haifar da samar da mafi girma platelets.

• Matsakaicin matakin platelet a cikin jini (yawan su) gabaɗaya tsakanin 150 zuwa 000 platelets a kowane milimita mai siffar sukari;
• The MPV, wanda ke auna girman su, sabili da haka ƙarar su, ana auna ta a cikin femtolites (nau'in ma'auni na girma daidai da 10).^-15% lita). A al'ada MPV is tsakanin mata 6 zuwa 10.

Ya kamata ku sani cewa platelets tare da mafi girma girma sun fi aiki. A ƙarshe, idan babu ilimin cututtuka, ana sarrafa jimlar adadin platelet, da ma'anar ma'anar platelet (MPV) don haka yakan tashi da zarar an saukar da adadin platelet.

Matsakaicin ƙarar platelet za a iya shafar shi dangane da wasu cututtukan ƙwayar cuta. Kuma shi ne, musamman, ingancin platelet wanda za'a iya canza shi a yayin da ba a saba ba MPV.

A lokacin thrombocytopenia, sabili da haka raguwar rashin daidaituwa a cikin adadin platelet, yana iya zama da amfani don saka idanu akan MPV, da kuma idan akwai thrombocytosis (ƙaramar adadin platelet) ko wasu thrombopathies (cututtukan da adadin platelet ya zama al'ada amma). aikin wanda ba daidai ba ne). 

The MPV Har ila yau da alama an haɗa shi musamman tare da haɗarin zuciya, wanda ya rage kadan a yi amfani da shi a aikace, saboda akwai matsalolin fasaha da ke tsoma baki tare da ma'auni. A gaskiya ma, lokacin da akwai haɗarin cututtukan zuciya ko haɗarin thrombosis, irin su phlebitis, ana iya danganta wannan tare da babba. MPV.

A cikin wannan ma'anar, ayyukan bincike da yawa da aka gudanar a cikin shekaru ashirin da suka gabata sun nuna cewa MPV zai zama mai ban sha'awa don samar da bayanai masu mahimmanci a cikin ci gaba da tsinkayen da suka shafi yanayin kumburi daban-daban. 

Don haka, wannan binciken ya nuna cewa a high MPV An lura da haɗin gwiwa tare da yawancin pathologies:

• Cututtukan zuciya da jijiyoyin jini;
• Bugun jini;
• Cututtukan numfashi;
• Rashin koda na kullum;
• Cututtukan hanji;
• Cututtukan rheumatoid;
• ciwon.
• Ciwon daji daban -daban.

Tattaunawa, a MPV ya ragu za a iya lura a lokuta masu zuwa:

• Tarin fuka, a lokacin ɓarkewar cutar;
• Ulcerative colitis;
• Tsarin tsarin lupus erythematosus a cikin manya;
• Cututtukan neoplastic daban -daban (haɓakar mahaifa da haɓaka sel).

Wannan shine dalilin da ya sa, daga ra'ayi na asibiti, zai zama mai ban sha'awa don kafa ƙimar kofa. MPV iya nuna, a tsakanin sauran abubuwa, da tsanani na wani kumburi tsari, gaban wata cuta, da kara hadarin kamuwa da cuta, da kara hadarin thrombotic rikitarwa, da kara hadarin mutuwa da kuma, a karshe, mai haƙuri ta mayar da martani ga jiyya. shafi. Koyaya, a cikin aikin asibiti, waɗannan amfani na MPV har yanzu suna da iyaka kuma suna buƙatar ƙarin bincike.

A gwajin jini mai sauƙi wajibi ne don nazarin ma'auni na platelet. Don haka, da MPV gabaɗaya ana aunawa yayin bincike akai-akai: ƙididdigar jini (ko CBC), cikakken gwajin jini wanda ya sa ya yiwu musamman a ƙidaya dukkan abubuwan da ke cikinsa (jajayen ƙwayoyin jini, fararen jini da platelets). A aikace, yana da kyau a dauki samfurin jini akan komai a ciki.

The MPV Ana gudanar da bincike, wanda aka yi akan bututun da aka ɗauka yayin gwajin jini, ta hanyar hanya mai sarrafa kanta, wacce aka yi amfani da ita tun shekarun 1970, kuma ana kiranta da “watsawar haske” a cikin Ingilishi:

• Ka'idar wannan jarrabawar ita ce haskaka sel tare da laser ko tungsten;
• Hasken da kowane sel ke watsawa na daukar hoton na'urar daukar hoto ne, daga nan sai ya rikide zuwa motsin lantarki;
• Don haka, mai nazarin zai iya lissafin matsakaicin adadin dubban platelet waɗanda ke yawo ta hanyar wuce su ta cikin katako;
• Lissafin ma'anar ma'aunin platelet, MPV, a ƙarshe ana yin ta ta hanyar jujjuyawar logarithmic na lanƙwan rarraba ƙarar platelet.

Don fassara sakamakon ƙarar ƙaramin platelet, yakamata koyaushe ku kasance da farko da farko an duba adadin platelet masu alaƙa da MPV. Wannan adadin platelets na iya raguwa idan an sami thrombocytopenia, ko akasin haka ya ƙaru idan akwai thrombocytosis.

• Un babban MPV yana nufin babban adadin manyan platelet suna yawo cikin jini;
• Un MPV tushe akasin haka, yana nufin cewa mutumin yana da adadi mai yawa na ƙananan platelet.

Yakamata koyaushe a bincika sakamakon daidai gwargwado tare da bayanan asibitin, amma kuma tare da sauran sakamakon ƙimar jini. Sau da yawa, sakamako mara kyau zai buƙaci ƙarin gwaji.

Bugu da ƙari, a ƙarƙashin wasu yanayi, platelet na iya haɗuwa tare. Sannan suna da alama suna nan a cikin adadi kaɗan ko kuma suna nuna an ƙara girman su: dole ne a ɗauki samfurin don bincika platelet kai tsaye a ƙarƙashin madubin microscope.

Daga qarshe:

• Dukda cewa a kashin kasusuwa ba za a iya kawar da shi ba a yanayin da ba a saba ba MPV, abubuwan da ba su haɗa da kasusuwa ba suma suna da yawa: kumburi cututtuka ou cututtukan autoimmune lalata platelets;
• Ƙananan thrombocytopenia (ƙananan yawan adadin platelets) wanda ke hade da ƙananan MPV yana da alaƙa da dakatar da samar da sel ta bargo: yana iya zama tambayaanemia. A ƙasa MPV Hakanan ana iya haɗa shi da sequestration wawa (a cikin sarkin) musamman tunda shine lokacin shine mafi girman platelet wanda aka ware;
• A cikin mutumin da ba shi da tarihin zub da jini na baya, kuma tare da adadin platelet na yau da kullun, mara kyau MPV yana da ƙarancin amfani na asibiti. Don haka MPV iya kawai bambanta daga physiological hanya, kuma ba tare da akwai wata alaƙa da kowace cuta ba.