Contents
Idiopathic fibrosing alveolitis (IFA) cuta ce da ta kasance ɗaya daga cikin mafi ƙarancin karatu, a tsakanin sauran cututtukan interstitium na huhu. Tare da irin wannan nau'in alveolitis, kumburi na interstitium na huhu yana faruwa tare da fibrosis. Wahala, gami da hanyoyin iska, parenchyma na huhu. Wannan mummunan yana rinjayar yanayin gabobin numfashi, yana haifar da canje-canje masu ƙuntatawa, rushewar musayar gas da gazawar numfashi, wanda ke haifar da mutuwa.
Idiopathic fibrosing alveolitis kuma ana kiransa fibrosis na huhu na idiopathic. Ana amfani da wannan ma'anar ta musamman ta ƙwararrun Ingilishi (idiopathic pulmonary fibrosis), da kuma masu ilimin huhu na Jamus (idiopa-thische Lungenfibrose). A cikin Burtaniya, ana kiran ELISA "cryptogenic fibrosing alveolitis" (cryptogenic fibrosing alveolitis).
Kalmomin "cryptogenic" da "idiopathic" suna da wasu bambance-bambance, amma yanzu ana amfani dasu. Duk waɗannan kalmomi biyu suna nufin cewa ba a san dalilin cutar ba.
Epidemiology da abubuwan haɗari
Bayanan kididdigar da ke nuna yaduwar cutar suna da sabani sosai. An ɗauka cewa irin waɗannan bambance-bambancen sun kasance ne saboda haɗakar da marasa lafiya ba kawai tare da fibrosing alveolitis na idiopathic ba, har ma tare da wasu cututtuka na interstitial pneumonias (IIP).
Daga cikin maza 100, mutane 000 suna fama da cututtukan cututtuka, kuma mutane 20 cikin 100 mata. A cikin shekara, mutane 000 suna fama da rashin lafiya ga kowane maza 13, kuma mutane 100 ga kowace mace 000.
Kodayake ba a san abubuwan da ke haifar da alveolitis na idiopathic a halin yanzu ba, masana kimiyya ba su daina ƙoƙarin gano ainihin asalin cutar ba. Akwai zato cewa Pathology yana da tushen kwayoyin halitta, lokacin da mutum yana da predisposition na gado ga samuwar fibrous kyallen takarda a cikin huhu. Wannan yana faruwa ne don mayar da martani ga duk wani lahani ga sel na tsarin numfashi. Masana kimiyya sun tabbatar da wannan hasashe tare da tarihin iyali, lokacin da aka gano wannan cuta a cikin dangin jini. Har ila yau a cikin ni'imar tushen kwayoyin cutar shine gaskiyar cewa fibrosis na huhu sau da yawa yana bayyana kansa a cikin marasa lafiya da cututtukan gado, alal misali, tare da cutar Gaucher.
Canje-canjen tsari a cikin huhu
Babban halaye na hoton morphological na idiopathic fibrosing alveolitis sune:
Kasancewar fibrosis mai yawa na parenchyma na huhu.
Ana rarraba canje-canjen ilimin dabi'a bisa ga nau'in nau'in nau'in nau'in nau'in nau'in nau'i. Irin wannan tabo yana faruwa ne saboda gaskiyar cewa wuraren lafiya da lalacewa na kyallen takarda suna canzawa a cikin huhu. Canje-canje na iya zama fibrous, cystic, kuma a cikin nau'i na kumburi na interstitial.
Babban ɓangare na acinus an haɗa shi da wuri a cikin tsarin kumburi.
Gabaɗaya, ilimin tarihin ƙwayar huhu a cikin idiopathic fibrosing alveolitis yayi kama da irin wannan hoto kamar a cikin ciwon huhu na tsaka-tsaki.
Alamomin idiopathic fibrosing alveolitis
Mafi sau da yawa, fibrosing idiopathic alveolitis an gano shi a cikin marasa lafiya da suka girmi shekaru 50. Maza sun fi mata rashin lafiya. Matsakaicin ma'auni shine 1,7:1.
Marasa lafiya suna nuna ƙarancin numfashi, wanda ke ƙaruwa koyaushe. Mai haƙuri ba zai iya yin numfashi mai zurfi ba (dyspnea mai ban sha'awa), yana fama da busassun tari ba tare da sputum ba. Dyspnea yana faruwa a duk marasa lafiya tare da idiopathic fibrosing alveolitis.
Ƙarfafa ƙarancin numfashi, mafi tsanani yanayin cutar. Bayan ya bayyana sau ɗaya, ba ya wucewa, amma yana ci gaba kawai. Bugu da ƙari, abin da ya faru ba ya dogara da lokacin rana, a kan yanayin zafi da sauran dalilai. An taqaitaccen matakai masu ban sha'awa a cikin marasa lafiya, da kuma matakan ƙarewa. Saboda haka, numfashin irin waɗannan marasa lafiya yana da sauri. Kowannen su yana da ciwon hawan jini.
Idan mutum yana son yin numfashi mai zurfi, to wannan yana haifar da tari. Duk da haka, ba duk marasa lafiya suna tasowa tari ba, don haka ba shi da sha'awar ganowa. Duk da yake a cikin mutanen da ke fama da cututtukan huhu na yau da kullun, wanda galibi ana rikicewa da ELISA, tari zai kasance koyaushe. Yayin da cutar ta ci gaba, ƙarancin numfashi yana haifar da gaskiyar cewa mutum ya zama nakasa. Ya rasa ikon furta dogon magana, ba zai iya tafiya ba kuma ya kula da kansa da kansa.
Ma'anar Pathology da kyar ake gani. Wasu marasa lafiya lura cewa fibrosing alveolitis ya fara tasowa a cikin su bisa ga irin SARS. Saboda haka, wasu masana kimiyya sun nuna cewa cutar na iya zama nau'in kwayar cuta. Tun da pathology yana tasowa a hankali, mutum yana da lokaci don daidaitawa da ƙarancin numfashi. Ba tare da sanin kansu ba, mutane suna rage ayyukansu kuma su ci gaba zuwa rayuwa mai mahimmanci.
Tari mai amfani, wato, tari wanda ke tare da samar da sputum, yana tasowa a cikin fiye da 20% na marasa lafiya. Ƙunƙarar na iya ƙunsar maƙarƙashiya, musamman ma a cikin waɗancan marasa lafiya waɗanda ke fama da tsananin idiopathic fibrosing alveolitis. Wannan alamar tana da haɗari, saboda yana nuna ƙarin kamuwa da ƙwayar cuta.
Ƙara yawan zafin jiki da bayyanar jini a cikin sputum ba su da irin wannan cuta. Yayin sauraron huhu, likita ya yi la'akari da crepitus da ke faruwa a ƙarshen wahayi. Idan jini ya bayyana a cikin sputum, ya kamata a tura majiyyaci don bincika ciwon huhu. Wannan cuta a cikin marasa lafiya tare da ELISA an gano shi sau 4-12 sau da yawa fiye da a cikin mutane masu lafiya, har ma da masu shan taba.
Sauran alamun ELISA sun haɗa da:
Haɗin gwiwa.
Ciwon tsoka.
Nakasar ƙusa phalanges wanda ya fara kama da ganguna. Wannan alamar tana faruwa a cikin 70% na marasa lafiya.
Crpitations a karshen inhalation ya zama mafi tsanani, kuma a farkon za su kasance mafi m. Kwararru suna kwatanta ƙirƙira ta ƙarshe zuwa fashewar cellophane ko sautin da ake yi lokacin da aka buɗe zik din.
Idan a farkon mataki na ci gaba da cutar, ana jin crpitations galibi a cikin yankunan basal na baya, sa'an nan yayin da yake ci gaba, za a ji creaks a duk faɗin huhu. Ba a ƙarshen numfashi ba, amma a duk tsawonsa. Lokacin da cutar ta fara tasowa, crepitus na iya zama ba ya nan lokacin da gangar jikin ta karkata gaba.
Ana jin raƙuman busassun ba fiye da 10% na marasa lafiya ba. Mafi na kowa dalilin shi ne mashako. Ci gaba da ci gaba da cutar yana haifar da bayyanar cututtuka na gazawar numfashi, ci gaban cor pulmonale. Launin fata yana samun launin ash-cyanotic, sautin na 2 a kan jijiya na huhu yana ƙaruwa, bugun zuciya yana saurin sauri, jijiyoyin mahaifa sun kumbura, gaɓoɓin gaɓoɓi. Mataki na ƙarshe na cutar yana haifar da asarar nauyi mai faɗi na mutum, har zuwa ci gaban cachexia.
Bincike na idiopathic fibrosing alveolitis
Hanyoyi don bincikar cututtukan fibrosing alveolitis a wannan lokacin an sake bitar. Ko da yake irin wannan fasaha na bincike a matsayin buɗaɗɗen ƙwayar huhu yana ba da sakamako mafi aminci kuma ana la'akari da "ma'auni na zinariya" na bincike, ba koyaushe ake yin shi ba.
Wannan shi ne saboda rashin amfani mai mahimmanci na buɗaɗɗen ƙwayar huhu, ciki har da: hanyar da ake amfani da ita, yana da tsada, bayan aiwatar da shi, magani zai buƙaci a jinkirta har sai mai haƙuri ya warke. Bugu da kari, ba zai yiwu a yi biopsy sau da yawa ba. Ba shi yiwuwa gaba ɗaya wani ɓangare na marasa lafiya su yi shi, tunda yanayin lafiyar ɗan adam bai yarda da shi ba.
Ma'auni na asali na bincike waɗanda aka haɓaka don gano alveolitis fibrosing idiopathic sune:
Sauran pathologies na interstitium na huhu an cire su. Wannan yana nufin cututtukan da za a iya haifar da su ta hanyar shan magunguna, shakar abubuwa masu cutarwa, lalata tsarin nama.
Ayyukan numfashi na waje yana raguwa, musayar gas a cikin huhu yana damuwa.
A lokacin gwajin CT, ana gano canje-canjen ragar raga a cikin huhu, a cikin sassansu na asali.
Wasu cututtuka ba a tabbatar da su ba bayan biopsy transbronchial ko bronchoalveolar lavage.
Ƙarin sharuɗɗan bincike sun haɗa da:
Mai haƙuri ya haura shekaru 50.
Rashin numfashi yana faruwa ba tare da fahimta ba ga mai haƙuri, yana ƙaruwa tare da motsa jiki.
Cutar tana da dogon lokaci (daga watanni 3 ko fiye).
Ana jin Crepitus a cikin yankunan basal na huhu.
Domin likita ya sami damar yin ganewar asali, wajibi ne a sami tabbaci na manyan ma'auni 4 da ƙarin 3. Kimanta ma'auni na asibiti yana ba da damar tantance ELISA tare da babban matakin yuwuwar, har zuwa 97% (bayanan da Raghu et al ya bayar), amma ƙwarewar ma'aunin kanta daidai yake da 62%. Saboda haka, kusan kashi uku na marasa lafiya har yanzu suna buƙatar yin biopsy na huhu.
Ƙididdigar ƙididdiga mai ƙima yana inganta ingancin gwajin huhu kuma yana sauƙaƙe ganewar asali na ELISA, da sauran cututtuka irin wannan. Darajar bincikensa yana daidai da 90%. Masana da yawa sun dage a kan watsi da kwayar cutar kwata-kwata, muddin dai ingantattun hotuna sun bayyana canje-canjen halayen alveolitis na idiopathic. A wannan yanayin, muna magana ne game da huhu na "zuma" (lokacin da yankin da aka shafa ya kasance 25%), da kuma tabbatar da tarihin tarihi na kasancewar fibrosis.
Binciken dakin gwaje-gwaje ba shi da wani mahimmanci a duniya dangane da gano cututtukan cututtuka.
Babban halayen binciken da aka samu:
Matsakaicin haɓaka a cikin ESR (wanda aka gano a cikin 90% na marasa lafiya). Idan ESR ya karu sosai, to wannan na iya nuna ciwon daji, ko kamuwa da cuta mai tsanani.
Ƙara cryoglobulins da immunoglobulins (a cikin 30-40% na marasa lafiya).
Haɓakawa a cikin abubuwan antinuclear da rheumatoid, amma ba tare da bayyanar cututtukan tsarin tsarin ba (a cikin 20-30% na marasa lafiya).
A karuwa a cikin jini matakin na jimlar lactate dehydrogenase, wanda shi ne saboda karuwar aiki na alveolar macrophages da nau'in 2 alveocytes.
Ƙara yawan hematocrit da jajayen ƙwayoyin jini.
A karuwa a matakin leukocytes. Wannan alamar na iya zama alamar kamuwa da cuta, ko alamar shan glucocorticosteroids.
Tun da fibrosing alveolitis yana haifar da rikice-rikice a cikin aiki na huhu, yana da mahimmanci a kimanta girman su, wato, ƙarfinsu mai mahimmanci, jimillar iyawa, ƙarar saura da ƙarfin aiki. Lokacin yin gwajin, ƙimar Tiffno za ta kasance cikin kewayon al'ada, ko ma karuwa. Binciken matsi-ƙarar lanƙwasa zai nuna motsinsa zuwa dama da ƙasa. Wannan yana nuna raguwar haɓakar huhu da raguwar ƙarar su.
Gwajin da aka kwatanta yana da matukar damuwa, don haka ana iya amfani da shi don farkon ganewar asali na ilimin cututtuka, lokacin da wasu nazarin ba su gano wani canje-canje ba. Misali, gwajin iskar gas na jini da aka yi a lokacin hutawa ba zai nuna wani rashin daidaituwa ba. Ana lura da raguwa a cikin ɓangaren tashin hankali na iskar oxygen a cikin jini na jijiya kawai a lokacin motsa jiki.
A nan gaba, hypoxemia zai kasance ko da a lokacin hutawa kuma yana tare da hypocapnia. Hypercapnia yana tasowa ne kawai a mataki na ƙarshe na cutar.
Lokacin gudanar da aikin rediyo, yawanci ana iya ganin canje-canje na nau'in reticular ko reticulonodular. Za a same su a cikin huhu biyu, a cikin ƙananan sashinsu.
Nama na baya tare da fibrosing alveolitis ya zama m, an kafa madauri a ciki, haskakawar cystic tare da diamita na 0,5-2 cm. Suna samar da hoton "hunhun zuma". Lokacin da cutar ta kai mataki na ƙarshe, yana yiwuwa a iya hangen nesa na ɓarna na trachea zuwa dama da tracheomegaly. A lokaci guda, ƙwararrun masana yakamata suyi la'akari da cewa a cikin 16% na marasa lafiya, hoton x-ray na iya kasancewa a cikin kewayon al'ada.
Idan pleura yana da hannu a cikin tsarin pathological a cikin majiyyaci, adenopathy na intrathoracic yana tasowa kuma an lura da kauri na parenchymal, to wannan na iya nuna rikitarwa na ELISA ta hanyar ciwon daji, ko wata cutar huhu. Idan majiyyaci a lokaci guda ya kamu da alveolitis da emphysema, to ƙarar huhu na iya kasancewa cikin kewayon al'ada, ko ma a ƙara. Wani alamar bincike na haɗuwa da waɗannan cututtuka guda biyu shine raunin tsarin jijiyoyin jini a cikin ɓangaren sama na huhu.
A lokacin babban ƙididdiga na ƙididdiga, likitoci sun gano alamun masu zuwa:
Inuwa madaidaiciya mara daidaituwa.
Cystic lucidity.
Mayar da hankali na rage bayyana gaskiya na filayen huhu na nau'in "gilashin sanyi". Yankin lalacewa ga huhu shine 30%, amma babu ƙari.
Thickening na ganuwar bronchi da rashin bin ka'ida.
Rashin tsari na parenchyma na huhu, traction bronchiectasis. Yankunan basal da subpleural na huhu sun fi shafa.
Idan ƙwararren ƙwararren ya kimanta bayanan CT, to, ganewar asali zai zama 90% daidai.
Wannan binciken ya ba da damar bambance tsakanin idiopathic fibrosing alveolitis da sauran cututtuka da ke da irin wannan hoto, ciki har da:
Na kullum hypersensitivity pneumonitis. Tare da wannan cuta, mai haƙuri ba shi da canje-canje na "salon salula" a cikin huhu, ƙananan nodules na centrilobular suna da hankali, kuma kumburi da kansa ya mayar da hankali a cikin babba da tsakiyar sassan huhu.
Asbestosis. A wannan yanayin, mai haƙuri yana tasowa plaques na pleural da parenchymal bands na fibrosis.
Desquamative interstitial pneumonia. Baƙi na nau'in "gilashin sanyi" za a tsawaita.
Bisa ga lissafta tomography, yana yiwuwa a yi tsinkaya ga mai haƙuri. Zai fi kyau ga marasa lafiya da ciwon gilashin ƙasa, kuma mafi muni ga marasa lafiya da canje-canje na reticular. Ana nuna tsinkayen tsaka-tsaki ga marasa lafiya tare da gauraye alamomi.
Wannan shi ne saboda gaskiyar cewa marasa lafiya tare da ciwon gilashin ƙasa sun amsa mafi kyau ga maganin glucocorticosteroid, wanda ke nunawa ta hanyar alamomi a lokacin HRCT. Yanzu likitoci sun fi jagoranci ta hanyar bayanan ƙididdiga yayin yin tsinkaye fiye da sauran hanyoyin (bronchial da alveolar lavage, gwajin huhu, biopsy huhu). An lissafta tomography wanda ya sa ya yiwu a tantance matakin shigar da parenchyma na huhu a cikin tsarin pathological. Yayin da biopsy ke ba da damar bincika wani yanki na jiki kawai.
Bronchoalveolar lavage bai kamata a cire shi daga aikin bincike ba, kamar yadda ya sa ya yiwu a ƙayyade tsinkayen ilimin cututtuka, tafarkinsa da kuma kasancewar kumburi. A cikin lavage tare da ELISA, an sami ƙarin adadin eosinophils da neutrophils. A lokaci guda, wannan alamar alama ce ta wasu cututtuka na ƙwayar huhu, don haka muhimmancinsa bai kamata a yi la'akari da shi ba.
Babban matakin eosinophils a cikin lavage yana cutar da tsinkayen fibrosing alveolitis na idiopathic. Gaskiyar ita ce, irin waɗannan marasa lafiya galibi suna ba da amsa mara kyau ga jiyya tare da magungunan corticosteroid. Amfani da su yana ba da damar rage matakin neutrophils, amma adadin eosinophils ya kasance iri ɗaya.
Idan an sami babban taro na lymphocytes a cikin ruwan lavage, wannan na iya nuna kyakkyawan hangen nesa. Tun da karuwar su sau da yawa yana faruwa tare da isasshen amsawar jiki don jiyya tare da corticosteroids.
Transbronchial biopsy yana ba ku damar samun ƙananan yanki na nama (ba fiye da 5 mm ba). Sabili da haka, an rage darajar bayanin karatun. Tun da wannan hanya yana da lafiya ga mai haƙuri, ana yin shi a farkon matakan cutar. Biopsy na iya ware cututtuka irin su sarcoidosis, hypersensitivity pneumonitis, ciwon daji, cututtuka, eosinophilic pneumonia, histocytosis, da alveolar proteinosis.
Kamar yadda aka ambata, wani buɗaɗɗen nau'in biopsy ana la'akari da hanyar gargajiya don bincikar ELISA, yana ba ku damar bincikar daidaitaccen bincike, amma ba shi yiwuwa a hango ci gaban cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan da kuma yadda ake yin amfani da wannan hanyar. Za'a iya maye gurbin buɗaɗɗen biopsy ta hanyar thoracoscopic biopsy.
Wannan binciken ya ƙunshi ɗaukar nau'in nau'in nau'in nau'in nama, amma tsawon lokacin magudanar ruwa na kogin pleural bai daɗe ba. Wannan yana rage lokacin da majiyyaci ke yi a asibiti. Matsaloli daga hanyar thoracoscopic ba su da yawa. Kamar yadda bincike ya nuna, buɗaɗɗen biopsy ba shi da kyau a rubuta wa duk marasa lafiya ba tare da togiya ba. Ana buƙatar gaske kawai ta 11-12% na marasa lafiya, amma ba ƙari ba.
A cikin rabe-raben cututtuka na duniya na bita na 10, an bayyana ELISA a matsayin "J 84.9 - Ciwon huhu na Interstitial, wanda ba a bayyana ba."
Za a iya tsara cutar ta kamar haka:
ELISA, matakin farko, gazawar numfashi na digiri na 1st.
ELISA a mataki na "hanyar salula", gazawar numfashi na digiri na 3, na kullum cor pulmonale.
Jiyya na idiopathic fibrosing alveolitis
Har yanzu ba a samar da ingantattun hanyoyin magance ELISA ba. Bugu da ƙari, yana da wuya a ba da ƙarshe game da tasiri na sakamakon farfadowa, tun da bayanai game da yanayin yanayin cutar ba su da yawa.
Jiyya ya dogara ne akan amfani da kwayoyi waɗanda ke rage amsawar kumburi. Ana amfani da Corticosteroids da cytostatics, wanda ke shafar tsarin garkuwar jikin mutum kuma yana taimakawa rage kumburi. An bayyana irin wannan maganin ta hanyar zato cewa idiopathic fibrosing alveolitis yana tasowa a kan tushen kumburi na kullum, wanda ya haɗa da fibrosis. Idan an kashe wannan dauki, to ana iya hana samuwar fibrotic canje-canje.
Akwai hanyoyi guda uku masu yuwuwar jiyya:
Jiyya tare da glucocorticosteroids kawai.
Jiyya tare da glucocorticosteroids tare da azathioprine.
Jiyya tare da glucocorticosteroids tare da cyclophosphamide.
Yarjejeniyar kasa da kasa, wanda aka gudanar a cikin 2000, ya ba da shawarar yin amfani da tsarin 2 na ƙarshe a cikin jiyya, kodayake babu wata hujja da ke goyon bayan tasirin su idan aka kwatanta da glucocorticosteroid monotherapy.
Yawancin likitoci a yau suna rubuta glucocorticosteroids don gudanar da baki. Duk da yake yana yiwuwa a cimma sakamako mai kyau kawai a cikin 15-20% na marasa lafiya. Mutanen da ba su da shekaru 50, yawanci mata, sun amsa mafi kyau ga irin wannan far idan sun ƙara darajar lymphocytes a cikin lavage daga bronchi da alveoli, kuma an gano canjin gilashin ƙasa.
Ya kamata a ci gaba da jiyya na akalla watanni shida. Don kimanta tasirinsa, kula da alamun cutar, sakamakon haskoki na x-ray da sauran fasaha. A lokacin jiyya, wajibi ne a kula da lafiyar mai haƙuri, tun da irin wannan maganin yana hade da babban haɗari na rikitarwa.
Akwai wasu masana da ke adawa da amfani da cytostatics a cikin maganin ELISA. Suna tabbatar da hakan ta hanyar cewa yuwuwar rikice-rikice tare da irin wannan jiyya yana da yawa. Wannan shi ne ainihin gaskiya game da amfani da Cyclophosphamide. Mafi yawan sakamako mai illa shine pancytopenia. Idan platelets sun faɗi ƙasa da 100/ml, ko kuma matakin lymphocytes ya faɗi ƙasa da 000/ml, to ana rage adadin magungunan.
Bugu da ƙari, leukopenia, jiyya tare da cyclophosphamide yana da alaƙa da ci gaban irin waɗannan sakamako masu illa kamar:
Ciwon mafitsara.
Hemorrhagic cystitis.
Stomatitis.
Rashin kujera.
Babban haɗari na jiki ga cututtuka masu yaduwa.
Idan duk da haka an wajabta majiyyacin cytostatics, to, kowane mako zai ba da gudummawar jini don cikakken bincike (a cikin kwanaki 30 na farko daga farkon jiyya). Sannan ana bada jini sau 1-2 a cikin kwanaki 14-28. Idan ana aiwatar da maganin ta hanyar amfani da Cyclophosphamide, to kowane mako mai haƙuri ya kamata ya kawo fitsari don bincike. Yana da mahimmanci a tantance yanayinta da sarrafa bayyanar jini a cikin fitsari. Irin wannan iko a cikin jiyya na gida na iya zama da wahala a aiwatar da shi, sabili da haka, irin wannan tsarin kulawa ba koyaushe ake amfani da shi ba.
Masana kimiyya suna fatan cewa yin amfani da interferon zai taimaka wajen jimre wa idiopathic fibrosing alveolitis. Suna hana germination na fibroblasts da matrix protein a cikin sel na huhu.
Hanya mai tsattsauran ra'ayi don magance cututtukan cututtuka ita ce dashen huhu. Rayuwar marasa lafiya a cikin shekaru 3 bayan tiyata shine 60%. Duk da haka, yawancin marasa lafiya tare da ELISA tsofaffi ne, don haka ba za su iya jure wa irin wannan shiga ba.
Maganin rikitarwa
Idan majiyyaci ya kamu da cutar ta numfashi, to an umarce shi da maganin rigakafi da antimycotics. Likitoci sun dage cewa a yi wa irin wadannan marasa lafiya allurar rigakafin mura da kamuwa da cutar pneumococcal. Ana aiwatar da maganin hauhawar jini na huhu da rashin daidaituwa na cor pulmonale bisa ga ka'idojin da suka dace.
Idan mai haƙuri ya bayyana hypoxemia, to ana nuna masa maganin oxygen. Wannan yana ba da damar rage ƙarancin numfashi da haɓaka haƙurin motsa jiki na mai haƙuri.
forecast
Hasashen a cikin marasa lafiya da idiopathic fibrosing alveolitis ba shi da kyau. Matsakaicin tsawon rai na irin waɗannan marasa lafiya bai wuce shekaru 2,9 ba.
Hasashen ya ɗan fi kyau a cikin mata marasa lafiya, a cikin matasa marasa lafiya, amma a yanayin cewa cutar ba ta wuce shekara ɗaya ba. Hakanan yana haɓaka hasashen sakamako mai kyau na jiki don jiyya tare da glucocorticosteroids.
Mafi sau da yawa, marasa lafiya suna mutuwa daga rashin ƙarfi na numfashi da na huhu. Wadannan matsalolin suna tasowa saboda ci gaban ELISA. Yana kuma iya zama m saboda ciwon huhu.