Le cortisol ne mai hormone steroid daga cholesterol da kuma ɓoye ta gland a saman kodan (da adrenal bawo). Sirrin sa yana dogara ne akan wani hormone, ACTH wanda glandan pituitary ya samar a cikin kwakwalwa (ACTH don adrenocorticotropin).

Cortisol yana taka rawa da yawa a cikin jiki, gami da:

• Metabolism na carbohydrates, lipids da sunadarai: yana taimakawa wajen daidaita sukarin jini ta hanyar haɓaka haɓakar glucose ta hanta (gluconeogenesis), amma kuma yana haɓaka sakin lipids da sunadarai a yawancin kyallen takarda.

• Yana da maganin kumburi

• Don daidaita hawan jini

• Zuwa girma kashi

• Amsar damuwa: Ana kiran Cortisol a matsayin hormone damuwa. Matsayinsa shine taimakawa jiki jurewa, ta hanyar tattara kuzarin da ake buƙata don ciyar da tsokoki, ƙwaƙwalwa amma har da zuciya.

Lura cewa matakin cortisol ya bambanta dangane da lokacin yini da dare: ya fi girma da safe kuma yana raguwa a cikin yini don isa matakin mafi ƙasƙanci da maraice.

Likita ya ba da umarnin a gwada matakin cortisol a cikin jini don bincika lalacewar glandan adrenal ko glandan pituitary. Ana auna Cortisol da ACTH a lokaci guda.

Jarabawar ta ƙunshi a gwajin jini, ana gudanar da shi da safe tsakanin 7 na safe zuwa 9 na safe Wannan shine lokacin da matakan cortisol ya kasance mafi girma kuma mafi kwanciyar hankali. Ma'aikatan kiwon lafiya da ke kula da binciken za su ciro jini mai jijiyoyi, yawanci daga ninkan gwiwar hannu.

Tunda matakan cortisol suna canzawa cikin yini, ana iya yin gwajin sau da yawa don samun ingantaccen hoto na matsakaicin samar da cortisol.

Hakanan za'a iya auna matakin cortisol a cikin fitsari (ma'auni na cortisol kyauta na fitsari, musamman mai amfani don gano hypersecretion na cortisol). Don yin wannan, dole ne a tattara fitsari a cikin akwati da aka tanadar don wannan dalili na tsawon sa'o'i 24.

Za mu bayyana muku hanyar, wanda gabaɗaya ya ƙunshi tattara dukkan fitsari na rana (ta adana shi a wuri mai sanyi).

Kafin yin gwaje-gwaje (jini ko fitsari), ana ba da shawarar a guji duk wani yanayi mai damuwa ko motsa jiki. Hakanan likita na iya neman dakatar da wasu jiyya waɗanda zasu iya yin tsangwama tare da adadin cortisol (estrogen, androgens, da sauransu).

A cikin jini, ƙimar al'ada na cortisol da aka tantance tsakanin 7 na safe zuwa 9 na safe yana tsakanin 5 zuwa 23 μg / dl (micrograms per deciliter).

A cikin fitsari, matakin cortisol wanda aka saba samu yana tsakanin 10 zuwa 100 μg / 24h (micrograms a kowace awa 24).

Babban matakan cortisol na iya zama alamar:

• Cushing ta ciwo (hawan jini, kiba, hyperglycemia, da dai sauransu).

• wani m ko m adrenal gland shine yake

• m kamuwa da cuta

• bugun jini na capsular, infarction na myocardial

• ko cirrhosis na hanta, ko yawan shan barasa

Akasin haka, ƙananan matakin cortisol na iya zama daidai da:

• rashin isasshen adrenal

• cutar addison

• rashin aiki na pituitary ko hypothalamus

• ko zama sakamakon tsawaita maganin corticosteroid

Likita ne kawai zai iya fassara sakamakon kuma ya ba ku ganewar asali (ƙarin gwaje-gwaje na wasu lokuta ya zama dole).