Har ila yau ana kiranta fetuin, thealpha-fetoprotein ne mai furotin ta hanyar halitta gwaiduwa jakar da kuma hanta du tayin a ci gaba. Ana samun sa a cikin jinin tayi da na uwa (lokacin daukar ciki). A cikin jarirai, adadinsa yana raguwa makonni kadan bayan haihuwa.

A cikin manya, alpha-fetoprotein na iya sake bayyana yayin wasu cututtuka, mafi yawan lokutan hanta ko ƙari.

Ana iya ba da nazarin alfa-fetoprotein ga mace yayin ciki ko ga manya a waje da ciki.

a lokacin ciki, Ana amfani da nazarin alpha-fetoprotein don gano asalin mahaifa daban-daban kuma ana yin shi a cikin watanni uku na biyu. Gwajin yawanci ya fi daidai tsakanin makonni 16 da 18. Nazarin alpha-fetoprotein yana faruwa lokaci guda tare da na ɗan adam chorionic gonadotropic hormone (HCG), estriol da inhibin A, hormones placental. Makasudin shine musamman don gano ɓarna na bututun jijiyoyin jiki (wanda zai zama tsarin juyayi) na tayin, kamar Spina bifida, amma kuma abubuwan rashin lafiyar chromosomal, kamar haɗarin trisomy 21 (ko Down's syndrome).

A cikin manya (ciki na waje), ana iya yin nazarin alpha-fetoprotein don gano matsalolin hanta ko gano wasu cututtukan daji.

Binciken alpha-fetoprotein ya ƙunshi wani gwajin jini a matakin jijiya kuma baya buƙatar takamaiman shiri. Likitan ya sanya abin zagayowar a hannun mai haƙuri, kusan 10 cm sama da wurin da za a yi jinya, yawanci a ƙashin gwiwar hannu.

A cikin mata masu juna biyu, wani sashi na alpha-fetoprotein da tayin ya samar yana shiga cikin jinin mahaifa, sabili da haka ba a buƙatar samin amniotic ko tayi. Ana ɗaukar samfurin jini ta hanyar “classic”.

A cikin manya, maza da mata a waje da lokacin daukar ciki, adadin alpha-fetoprotein na al'ada bai wuce 10 ng / ml na jini ba.

Haɓaka matakin alpha-fetoprotein a cikin jini na iya bayyana:

• ciwon hanta, kamar cirrhosis, za a ciwon daji, da ciwon hanta na giya ko don cutar hepatitis

• un ciwon daji goro, ovaries, ciki, pancreas ko bile ducts.

A cikin mata masu juna biyu, a cikin watanni uku na biyu, matakin alpha-fetoprotein yawanci tsakanin 10 zuwa 200 ng / ml. Babban matakan alpha-fetoprotein na iya haifar da:

• lahani na bututun jijiya a cikin tayi mai tasowa: Spina bifida, anencephaly

• lalacewar jijiya

• hydroencephaly

• lalacewar esophagus ko kodan

Sabanin haka, ƙaramin matakin na iya zama alamar rashin lafiyar chromosomal kamar Down syndrome (trisomy 21).

Yi hankali, duk da haka, matakin alpha-fetoprotein ya bambanta yayin daukar ciki. Don haka yana da mahimmanci a san madaidaicin matakin ciki wanda mace ke ciki yayin gwajin. Sakamakon alpha-fetoprotein mara kyau na iya kasancewa saboda yawan ciki ko mutuwar tayi.

Don haka ƙarin gwaje-gwaje ya zama dole a yayin matakan alpha-fetoprotein mahaukaci, kamar duban dan tayi ko amniocentesis (cire ruwan amniotic da ke kewaye da tayin).