Agranulocytosis wani cuta ne na jini wanda ke nuna bacewar wani nau'i na leukocytes: neutrophilic granulocytes. Ganin mahimmancin su a cikin tsarin rigakafi, bacewar su yana buƙatar gaggawar magani.

Agranulocytosis kalma ce ta likita da ake amfani da ita don komawa ga rashin daidaituwa na jini. Ya yi daidai da kusan bacewar granulocytes neutrophil na jini, wanda a da aka sani da neutrophils na jini.

Wadannan sassan jini su ne rukuni na leukocytes (fararen jini), kwayoyin jini da ke cikin tsarin rigakafi. Wannan rukunin kuma yana wakiltar mafi yawan leukocytes a cikin jini. A cikin jini, neutrophil granulocytes suna taka muhimmiyar rawa saboda suna da alhakin kariya daga jikin waje da ƙwayoyin cuta. Suna iya yin phagocyte waɗannan barbashi, wato a shanye su don halaka su.

Agranulocytosis shine rashin daidaituwa na jini wanda za'a iya gano shi tare da a haemogram, wanda kuma ake kira Ƙididdiga na Jini da Formula (NFS). Wannan gwajin yana ba da bayanai da yawa game da ƙwayoyin jini. Ƙididdiga na jini ya sa ya yiwu musamman don ƙididdige abubuwa daban-daban na jini, wanda neutrophil granulocytes ke cikin su.

A lokacin'neutrophil bincike, ana lura da rashin daidaituwa lokacin da yawan ƙwayar waɗannan ƙwayoyin ya kasance ƙasa da 1700 / mm3, ko 1,7 g / L a cikin jini. Idan matakin granulocytes neutrophilic ya yi ƙasa sosai, muna magana akan a neutropenia.

Agranulocytosis wani nau'i ne mai tsanani na neutropenia. An kwatanta shi da ƙananan matakin neutrophilic granulocytes, ƙasa da 500 / mm3, ko 0,5 g / L.

A mafi yawancin lokuta, agranulocytosis shine rashin daidaituwa na jini wanda ke faruwa bayan shan wasu magunguna. Dangane da asali da halaye na anomaly, akwai gabaɗaya nau'ikan agranulocytosis iri biyu:

• agranulocytosis mai tsanani na miyagun ƙwayoyi, ci gaban wanda ya faru ne saboda zaɓin guba na miyagun ƙwayoyi, wanda ke rinjayar kawai layin granulocyte;
• agranulocytosis da aka haifar da miyagun ƙwayoyi a cikin mahallin anemia aplastic, ci gaban wanda ya faru ne saboda rashin lafiya a cikin kasusuwan kasusuwa, wanda ke da alaƙa da raguwar ƙwayoyin jini da dama.

A cikin mahallin anemia na aplastic, kuma yana yiwuwa a rarrabe nau'ikan agranulocytosis da yawa. Lalle ne, wannan cutar ta jini da ke da katsewa a cikin samar da kwayoyin jini a cikin kasusuwa na iya samun asali da yawa. Ana iya la'akari da anemia aplastic kamar:

• post-chemotherapy aplastic anemia lokacin biye da maganin chemotherapy;
• na bazata aplastic anemia lokacin da wasu kwayoyi ke haifar da su.

Yayin da agranulocytosis da aka haifar da miyagun ƙwayoyi yana wakiltar tsakanin 64 da 83% na lokuta, waɗannan rashin daidaituwa na iya samun wasu dalilai. Na asali na kwayan cuta, hoto ko bidiyo mai zagaya yanar gizo da sauri, kamuwa da cuta a matakin ci gaba na iya haifar da raguwar granulocytes neutrophilic.

Idan aka ba da gudummawar neutrophilic granuclocytes a cikin tsarin rigakafi, agranulocytosis yana fallasa kwayoyin halitta zuwa babban haɗarin kamuwa da cuta. Neutrophils ba su da yawa isa don tsayayya da ci gaban wasu ƙwayoyin cuta, wanda zai iya haifar da a cutar sanƙarau, ko sepsis, kamuwa da cuta gaba ɗaya ko kumburin jiki.

Alamun agranulocytosis sune na kamuwa da cuta. Yana iya bayyana kansa ta alamun cututtuka a yankuna da dama na jiki ciki har da tsarin narkewa, tsarin ENT, tsarin huhu ko ma fata.

Agranulocytosis mai saurin ƙwayar cuta yana bayyana ba zato ba tsammani kuma yana bayyana ta hanyar barkewar zazzabi mai zafi (fiye da 38,5 ° C) tare da sanyi. A cikin marrow aplasia, ci gaban agranulocytosis na iya zama a hankali.

Agranulocytosis wata cuta ce ta jini wacce ke buƙatar yin magani da sauri don guje wa rikitarwa. Kodayake jiyya na iya bambanta dangane da asalin agranulocytosis, sarrafa shi gabaɗaya ya dogara ne akan:

• warewa a asibiti don kare majiyyaci;
• fara maganin rigakafi don magance cututtuka;
• Yin amfani da abubuwan haɓakar granulocyte don haɓaka samar da granulocytes neutrophilic.