Fecal elastase wani enzyme ne da pancreas ke samarwa wanda ke taka rawa wajen narkewa. Matsakaicin sa yana ba da damar kimanta aikin da ya dace na aikin pancreas da ke hade da narkewa.

Pancreas wani bangare ne na jikin mutum wanda ke da ayyuka guda biyu:

• aikin endocrine na kashi 10% na sel: pancreas yana ɓoye insulin da glucagon, hormones biyu waɗanda ke kula da daidaita matakin sukari a cikin jini. Insulin yana rage sukarin jini yayin da glucagon ke ƙaruwa. Wadannan hormones guda biyu suna taimakawa wajen daidaita matakan sukari na jini. Idan akwai matsala game da fitar insulin, muna magana game da ciwon sukari;
• aikin exocrine na 90% na sel: by Kwayoyin acinar, pancreas yana ɓoye enzymes na pancreatic, sunadaran da ke da takamaiman matsayi. Wadannan enzymes wani bangare ne na ruwan 'ya'yan itace na pancreatic kuma suna da mahimmanci don narkewar abinci mai kyau. Ta hanyar nuna son kai na tashoshi na Wirsung da Santorini, ruwan 'ya'yan itacen pancreatic yana barin pancreas ya zo ya haɗu da bile a cikin hanji. A cikin sashin narkewar abinci, waɗannan enzymes suna shiga cikin narkewar fats, sunadarai da carbohydrates ta hanyar wargaza su cikin abubuwa da yawa, mafi sauƙi da jiki ke haɗa su.

Fecal elastase yana daya daga cikin enzymes da pancreas ke samarwa. Ana samar da shi a cikin kwanciyar hankali kuma akai-akai, wanda ya sa ya zama alamar pancreatic mai kyau. Dalilin gwajin elastase na fecal shine don tantance aikin da ya dace na aikin exocrine na pancreas. Ƙimar ma'anar ita ce gram 200 a kowace gram na stool a cikin manya da yara (daga wata ɗaya). Wannan darajar tana da ƙarfi kuma tana ɗan bambanta kaɗan daga wannan rana zuwa wani a cikin mutum ɗaya sai dai idan akwai matsananciyar gudawa wanda ke lalata matakin elastase na fecal. A wannan yanayin, dole ne a maimaita bincike. Gwaji ne mai sauƙi don yin, wanda ke ba da damar maye gurbin shi don wasu gwaje-gwaje masu wahala kamar nazarin steatorrhea.

Ana yin wannan gwajin don tantance aikin exocrine na pancreas. Ana iya yin shi alal misali a yayin da ake tuhuma na rashin isasshen pancreatic exocrine. Hakanan ana iya buƙatar likita don sanin abubuwan da ke haifar da matsalar gudawa mai tsayi.

Ana yin ƙayyadaddun ƙayyadaddun elastase na faecal akan samfurin stool. Mai haƙuri zai iya tattara samfurin a gidansa tare da kayan da aka bayar ta dakin gwaje-gwaje na likita. Daga nan zai sauke samfurin a cikin dakin gwaje-gwaje don bincike da sauri. Ya kamata a adana samfurin a 4 ° C (a cikin firiji). Ya kamata a yi nazarin a cikin sa'o'i 48 na tarin stool. Wannan gwajin ELISA nau'in sanwici ne, musamman don elastase na ɗan adam (elastase E1). Wannan gwajin ya ƙunshi keɓance furotin tsakanin ƙwayoyin rigakafi guda biyu, kowanne yana gane wani yanki na furotin, don haka yana ba da damar ganowa da ƙidaya shi.

Idan mai haƙuri ya sami ƙarin maganin maye gurbin enzyme, wannan ba shi da tasiri akan adadin elastase na fecal. Sabanin haka, ya kamata a guji wasu abubuwa satin da ya gabata da kuma ranar samfurin:

• gwaje-gwaje na rediyo na narkewa;
• shirye-shirye don colonoscopy;
• laxatives;
• rigar hanji ko maganin zawo. Lallai, waɗannan abubuwan zasu iya canza furen hanji ko kuma gurbata sakamakon binciken.

Hakanan, yana da kyau a guje wa, idan zai yiwu, wannan gwajin yayin zawo mai tsanani. Idan wannan ba zai yiwu ba, ya kamata a nuna shi don likita ya yi la'akari da shi lokacin nazarin sakamakon.

Karancin matakin elastase na fecal (sai dai idan akwai gudawa) yana nuna gazawar aikin exocrine na pancreas. Matsakaicin taro tsakanin 150 zuwa 200 μg/g alama ce ta matsakaicin ƙarancin ƙarancin ƙwayar cuta na exocrine. Muna magana game da rashin wadatar pancreatic na exocrine lokacin da matakin elastase na fecal ya kasance ƙasa da 15 μg / g.

Daga nan, likita zai buƙaci yin ƙarin gwaje-gwaje, gwaje-gwaje da hotuna don sanin dalilin wannan rashin isa. Akwai dama da yawa:

• na kullum pancreatitis;
• m pancreatitis;
• cystic fibrosis;
• ciwon sukari;
• cutar celiac;
• Cutar Crohn;
• Zollinger-Ellison ciwo;
• tiyata na sama mai narkewa;
• da dai sauransu.