Anaplastic oligoastrocytoma, ko anaplastic astrocytoma, wani mummunan kumburi ne na kwakwalwa. Ya fi daidai glioma, wato ciwace-ciwacen da ke fitowa daga nama mai juyayi, a cikin kwakwalwa ko kashin baya. Hukumar Lafiya ta Duniya tana rarraba gliomas daga I zuwa IV, ya danganta da yanayin halittarsu da matakin rashin lafiya. Anaplastic astrocytomas suna wakiltar aji III, tsakanin maki I da II ana ɗaukar benign da glioblastomas (aji IV). Anaplastic astrocytoma iya ko dai zama mai wahala na wani benign sa II ƙari ko ci gaba spontaneously. Yana da ƙaƙƙarfan hali na ci gaba zuwa glioblastoma (aji IV) kuma tsawon rayuwa yana kusa da shekaru biyu zuwa uku, duk da jiyya tare da tiyata da radiotherapy / chemotherapy. Anaplastic astrocytomas da glioblastomas suna shafar 5 zuwa 8 a cikin mutane 100 a cikin yawan jama'a. (000)

Yawancin alamun anaplastic oligoastrocytoma suna haifar da karuwar matsa lamba a cikin kwakwalwa, wanda ya haifar da ko dai ta hanyar ciwace-ciwacen da kanta ko kuma ta hanyar haɓakar ruwa na cerebrospinal wanda ya haifar. Alamun sun bambanta dangane da ainihin wuri da girman ƙwayar cutar:

• Ƙwaƙwalwar ƙwaƙwalwa, canje-canjen hali da hemiplegia lokacin da ciwon daji ya girma a cikin lobe na gaba;
• Kamewa, ƙarancin ƙwaƙwalwar ajiya, daidaitawa da magana lokacin da ke cikin lobe na ɗan lokaci;
• Rikicin mota da rashin hankali (tingling da konewa) lokacin da yake cikin lobe na parietal;
• Hatsarin gani lokacin da ƙari ya ƙunshi lobe na occipital.

Ba a san ainihin dalilin anaplastic astrocytoma ba tukuna, amma masu bincike sun yi imanin cewa yana samuwa ne daga haɗuwa da kwayoyin halitta da abubuwan muhalli da ke haifar da cutar.

Anaplastic oligoastrocytoma ya fi kowa yawa a cikin maza fiye da mata kuma sau da yawa yana faruwa tsakanin shekaru 30 zuwa 50. Ya kamata a lura, duk da haka, cewa cutar na iya shafar yara, yawanci tsakanin 5 zuwa 9 shekaru. Anaplastic astrocytomas da multiform glioblastomas (maki III da IV) suna wakiltar kusan 10% na ciwace-ciwacen yara a cikin tsarin juyayi na tsakiya (80% na waɗannan ciwace-ciwacen suna aji I ko II). (1)

Cututtukan gado na gado irin su neurofibromatosis nau'in I (cutar Recklinghausen), ciwo na Li-Fraumeni, da Bourneville tuberous sclerosis suna ƙara haɗarin haɓaka astrocytoma na anaplastic.

Kamar yadda yake da ciwon daji da yawa, abubuwan muhalli kamar fallasa ga haskoki na ultraviolet, ionizing radiation da wasu sinadarai, da rashin abinci mai kyau da damuwa ana ɗaukar su abubuwan haɗari.

Maganin anaplastic oligoastrocytoma ya dogara da gaske akan yanayin gaba ɗaya na mai haƙuri, wurin da ƙari da saurin ci gaba. Ya ƙunshi tiyata, radiotherapy da chemotherapy, kadai ko a hade. Mataki na farko shine a cire babban ɓangaren ƙwayar cuta kamar yadda zai yiwu (resection), amma wannan ba koyaushe yana yiwuwa ba saboda sigogin da aka ambata a sama. Bayan tiyata, ana amfani da maganin radiation da yuwuwar chemotherapy don ƙoƙarin cire ragowar ƙari, misali idan ƙwayoyin cuta sun bazu cikin nama na kwakwalwa.

Hasashen yana da alaƙa da yanayin lafiyar majiyyaci, halayen ƙwayar cuta, da kuma martanin da jiki ke bayarwa game da chemotherapy da jiyya na rediyo. Anaplastic astrocytoma yana da ƙaƙƙarfan hali na ci gaba zuwa glioblastoma a cikin kimanin shekaru biyu. Tare da daidaitaccen magani, lokacin rayuwa na tsaka-tsaki ga mutanen da ke da astrocytoma anaplastic shine shekaru biyu zuwa uku, wanda ke nufin cewa rabinsu zasu mutu kafin wannan lokacin. (2)