A lokaci Sibo tsaye ga "kananan hanji kwayan overgrowth" kuma tana nufin wani kwayan overgrowth na kananan hanji, wanda aka halin an wuce kima yawan kwayoyin cuta a cikin wannan ɓangare na hanji da kuma malabsorption. Alamun asibiti na yau da kullun sune zawo, gas da alamun malabsorption. Abubuwan da ke haifar da haɓakar ƙwayoyin cuta sune ko dai anatomical (diverticulosis, madauki makafi, da dai sauransu) ko aiki (damuwa a cikin motsin hanji, rashin ɓoyewar acid na ciki). Jiyya ta ƙunshi babban kitse, abinci mai ƙarancin carbohydrate, kula da nakasa, maganin ƙwayoyin cuta mai faɗi, da kawar da abubuwan da ke ba da gudummawa don hana sake dawowa.

Kalmar SIBO tana nufin "ƙananan ƙwayar ƙwayar cuta ta hanji" ko ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta. An san shi da yawan ƙwayoyin cuta a cikin ƙananan hanji (> 105 / ml) wanda zai iya haifar da rikicewar malabsorption, watau rashin isasshen sha na abubuwan abinci.

A karkashin yanayi na al'ada, kusancin ƙaramin hanji yana ɗauke da ƙasa da ƙwayoyin cuta 105 / ml, galibi ƙwayoyin cuta masu cutar Gram-tabbatacce. Ana kiyaye wannan ƙananan ƙwayar ƙwayar cuta ta hanyar:

• sakamako na kumburin hanji na al'ada (ko peristalsis);
• al'ada acid secretion;
• gamsai;
• immunoglobulins na sirri;
• wani bawul na gidaocecal mai aiki.

Idan ƙwayar ƙwayar ƙwayar cuta, yawan ƙwayoyin cuta,> 105 / ml, ana samun su a cikin hanjin da ke kusa. Ana iya haɗa wannan zuwa:

• munanan abubuwa ko canje-canje na jikin mutum a cikin ciki da / ko ƙaramin hanji (diverticulosis na ƙananan hanji, madafan makafi na tiyata, yanayin bayan-gastrectomy, ƙuntatawa ko shinge na gefe) waɗanda ke haɓaka jinkirin abubuwan ciki, wanda ke haifar da haɓaka ƙwayar cuta; 
• rikicewar motsi na narkar da abinci wanda ke da alaƙa da ciwon sukari neuropathy, scleroderma, amyloidosis, hypothyroidism ko idiopathic intse pseudo-obstruction wanda kuma yana iya rage fitowar ƙwayoyin cuta;
• rashi na ɓarkewar acid na ciki (achlorhydria), wanda na iya zama na magani ko asalin tiyata.

Mafi yawan nau'in nau'in ƙwayoyin cuta don haɓakar ƙwayoyin cuta a cikin ƙananan hanji sun haɗa da:

• Streptococcus sp;
• Bacteroides sp;
• Escherichia coli;
• Staphylococcus sp;
• Klebsiella sp ;
• da Lactobacillus.

Waɗannan ƙananan ƙwayoyin cuta suna rage ƙarfin sha na ƙwayoyin hanji kuma suna cin abubuwan gina jiki, gami da carbohydrates da bitamin B12, wanda zai iya haifar da malabsorption na carbohydrate da rashin abinci mai gina jiki da rashi na bitamin. Haka kuma, waɗannan ƙwayoyin cuta kuma suna aiki akan gishiri bile ta hanyar canza su, suna hana samuwar micelles wanda ke haifar da malabsorption na lipids. Mummunan girma na ƙwayoyin cuta a ƙarshe yana haifar da raunuka na mucosa na hanji. 

Yawancin marasa lafiya ba su da alamun cutar. Baya ga asarar nauyi na farko ko rashi a cikin abubuwan gina jiki da bitamin mai narkewa (musamman bitamin A da D), alamun da aka fi sani sun haɗa da:

• rashin jin daɗi na ciki;
• yawan zawo mai yawa ko ;asa;
• steatorrhea, wato, yawan adadin lipids a cikin stool mara kyau, wanda ya samo asali ne daga malabsorption na lipids da lalacewa ga mucous membranes;
• kumburin ciki;
• iskar gas mai yawa, wanda ke haifar da iskar gas wanda ke haifar da haɓakar carbohydrates.

Dole ne a sanya maganin ƙwayoyin cuta, ba don kawar da ƙwayoyin ƙwayoyin cuta ba amma don canza shi don samun ingantacciyar alamun. Dangane da yanayin polymicrobial na flora na hanji, maganin rigakafi mai faɗi ya zama dole don rufe duk ƙwayoyin cuta na iska da na anaerobic.

Maganin SIBO don haka ya dogara ne akan shan, na kwanaki 10 zuwa 14, a baki, ɗaya ko biyu daga cikin maganin rigakafi masu zuwa:

• Amoxicillin / clavulanic acid 500 MG sau 3 / rana;
• Cephalexin 250 MG sau 4 / rana;
• Trimethoprim / sulfamethoxazole 160 mg / 800 MG sau biyu / rana;
• Metronidazole 250 zuwa 500 MG sau 3 ko sau 4 a rana;
• Rifaximin 550 MG sau 3 a rana.

Wannan maganin ƙwayoyin cuta mai faɗin bakan na iya zama cyclical ko ma an canza shi, idan alamun sun saba bayyana.

A lokaci guda, dole ne a kawar da abubuwan da ke fifita ƙwayar cuta ta kwayan cuta (ɓarna da ɓarna na aiki) kuma ana ba da shawarar gyara abincin. Lallai, ƙwayoyin cuta da suka wuce gona da iri suna haɓaka carbohydrates a cikin lumen na hanji maimakon lipids, ana ba da shawarar abinci mai yawan kitse da ƙarancin fiber da carbohydrate - babu lactose - an ba da shawarar. Dole ne a gyara raunin bitamin, musamman bitamin B12.