Purpura fulminans ciwo ne mai kamuwa da cuta wanda ke wakiltar wani nau'i mai tsanani na sepsis. Yana haifar da jini zuwa gudan jini da necrosis na nama. Sau da yawa cutar sankarau ce ke haifar da ita kuma sakamakonsa yana da mutuwa idan ba a kula da shi cikin lokaci ba.

Zazzaɓi mai zafi, babban lahani na yanayin gaba ɗaya, amai da ciwon ciki sune alamun farko marasa alama. Daya ko fiye ja da shunayya spots yada sauri a kan fata, sau da yawa a kan ƙananan gaɓoɓi. Wannan shi ne purpura, ciwon jini na fata. Matsi a kan fata ba ya zubar da jini kuma baya sa tabon ya ɓace na ɗan lokaci, alamar "ƙara" na jini a cikin kyallen takarda. Wannan shi ne saboda Purpura Fulminans yana haifar da yaduwar coagulation na intravascular (DIC), wanda shine samuwar ƙananan ƙwanƙwasa wanda zai rushe jini (thrombosis), yana jagorantar shi zuwa dermis kuma yana haifar da zubar jini da necrosis na nama na fata. Cutar cututtuka na iya kasancewa tare da yanayin girgiza ko damuwa na sanin wanda abin ya shafa.

A mafi yawancin lokuta, purpura fulminans suna da alaƙa da kamuwa da kamuwa da cuta mai tsanani. Neisseria meningitidis (meningococcus) shine mafi yawan kamuwa da cuta wanda ke da hannu, yana lissafin kusan kashi 75% na lokuta. Haɗarin haɓaka purpura fulminans yana faruwa a cikin kashi 30% na cututtukan meningococcal masu haɗari (IIMs). (2) 1 zuwa 2 lokuta na IMD a cikin mazaunan 100 suna faruwa kowace shekara a Faransa, tare da adadin masu mutuwa kusan 000%. (10)

Wasu magungunan ƙwayoyin cuta na iya zama alhakin haɓakar purpura fulminans, kamar Streptococcus pneumoniae (pneumococcus) ko Haemophilus mura (Pfeiffer's bacillus). Wani lokaci abin da ke haifar da shi shine rashi a cikin furotin C ko S, wanda ke taka rawa a cikin coagulation, saboda rashin daidaituwa na kwayoyin halitta: maye gurbi na PROS1 gene (3q11-q11.2) don furotin C da PROC gene (2q13-q14). don furotin C. Ya kamata a lura cewa purpura fulgurans na iya haifar da kamuwa da cuta mai laushi kamar kajin kaji, a lokuta masu wuyar gaske.

Purpura fulminans na iya shafar kowane shekaru, amma jarirai a ƙarƙashin shekara 15 da matasa masu shekaru 20 zuwa 1 suna cikin haɗari mafi girma. (XNUMX) Mutanen da ke da kusanci da wanda aka azabtar ya kamata su sami maganin rigakafi don hana duk wani hadarin kamuwa da cuta.

Hasashen yana da alaƙa kai tsaye da lokacin da aka ɗauka don ɗaukar nauyi. Purpura fulminans hakika yana wakiltar yanayin asibiti na matsananciyar gaggawa wanda ke buƙatar maganin rigakafi da wuri-wuri, ba tare da jiran tabbatar da ganewar asali ba kuma ba a gabatar da sakamakon farko na al'adar jini ko gwajin jini ba. Purpura wanda ya ƙunshi aƙalla wuri ɗaya tare da diamita mafi girma ko daidai da milimita 3, yakamata ya fara faɗakarwa da jiyya nan da nan. Maganin rigakafi ya kamata ya dace da cututtuka na meningococcal kuma a yi shi ta hanyar jini ko, rashin haka, a cikin tsoka.